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Table 1 ARDS patients’ characteristics

From: Feasibility, reproducibility and diagnostic usefulness of right ventricular strain by 2-dimensional speckle-tracking echocardiography in ARDS patients: the ARD strain study

ParametersARDS cohort (n = 48)D28 ARDS survivors (n = 36)D28 ARDS non-survivors (n = 12)Comparison survivors vs non-survivors
Sex (M, %)27 (56%)22 (61.1%)5 (41.7%)0.24 (Chi2)
Age (years)61 ± 1758 ± 1768 ± 140.25
SOFA8 [7;11]8 [7;11]10 [8;14]0.09 (MW)
SAPS II57 ± 1556 ± 1660 ± 140.49
Weight (kg)75.7 ± 20.379.5 ± 21.264.4 ± 12.10.02
Circulatory parameters
 SAP/MAP/DAP mmHg114 ± 19/77 ± 10/57 ± 9114 ± 16/78 ± 10/59 ± 9114 ± 28/72 ± 11/51 ± 80.99/0.10/0.01
 Heart rate bpm95 ± 2295 ± 2395 ± 190.97
 Sinus rhythm42 (87.5%)31 (86.1%)11 (91.7%)0.61 (Chi2)
Ventilator settings
 Tidal volume, ml/kg of IBW6.9 ± 1.16.9 ± 1.26.8 ± 0.80.74
 PEEP cmH2O10.6 ± 2.99.8 ± 2.610.2 ± 2.90.65
 Autopeep cmH2O0.8 ± 1.20.9 ± 1.30.5 ± 0.70.31
 Plateau pressure cmH2O23.2 ± 4.422.6 ± 4.324.3 ± 4.50.25
 Driving pressurecmH2O12.4 ± 4.111.8 ± 4.113.7 ± 3.90.19
 Respiratory rate/min24.0 ± 3.523.3 ± 3.425.5 ± 3.80.01
Arterial blood gases
 FiO2 (%)70 ± 2167 ± 1979 ± 250.10
 pH7.31 ± 0.147.34 ± 0.137.23 ± 0.160.01
 pCO2 mmHg45.6 ± 11.145.6 ± 12.145.7 ± 7.40.96
 pO2 mmHg83.6 ± 32.881.1 ± 24.191.3 ± 51.70.36
 HCO3-mmol22.1 ± 6.123.1 ± 5.919.1 ± 5.80.05
 SaO2%93.5 ± 5.094.0 ± 2.891.9 ± 8.90.20
 Lactate mmol2.1 ± 2.41.4 ± 0.93.9 ± 4.00.002
 PaO2:FiO2 ratio126 ± 48127 ± 46123 ± 550.77
Treatments in ICU
 Vasopressor support32 (66.7%)21 (58.3%)11 (91.7%)0.03 (Chi2)
 Inotropic support6 (12.5%)2 (5.6%)4 (33.3%)0.01 (Chi2)
 Neuromuscular blockade > 24 h30 (62.5%)25 (69.4%)9 (75%)0.71 (Chi2)
 Prone positioning18 (37.5%)15 (41.7%)3 (25%)0.30 (Chi2)
 Inhaled NO6 (12.5%)3 (8.3%)3 (25%)0.13 (Chi2)
 VV ECMO2 (4.2%)1 (2.8%)1 (8.3%)0.10 (Chi2)
 Renal replacement therapy12 (25%)9 (25%)3 (25%)1.00 (Chi2)
Outcome
 Mortality D28 n (%)12 (25%) 
 Mortality D90 n (%)14 (29.2%) 
 D28 ventilator-free days20.0 [1.3; 23.0]20.5 [14.3; 23.8]0 [0; 5.25]0.003 (MW)
  1. Median [interquartile range]; mean ± standard deviation; number (percentage)
  2. Statistical test: Student’s t test unless specified: MW, Mann–Whitney or Pearson Chi2
  3. SOFA sequential organ failure assessment, SAPS II Simplified Acute Physiology Score II, SAP–MAP–DAP systolic–mean–diastolic arterial pressure, IBW ideal body weight; PEEP: positive end-expiratory pressure, NO nitric oxide, VV ECMO veno-venous extracorporeal membrane oxygenation
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