Outcome/subgroup | No. of studies | No. of patients | Pooled mean difference (95% CI) | I2 (%) | P for subgroup difference |
---|---|---|---|---|---|
ICU LOS | Â | Â | Â | Â | Â |
 Population |  |  |  |  | 0.518 |
  Medical | 1 | 488 | 1.00 (− 0.91 to 2.91) | 0 |  |
  Surgical | 1 | 231 | − 0.50 (− 4.65 to 3.65) | 0 |  |
  Mixed | 4 | 943 | − 0.35 (− 1.77 to 1.08) | 0 |  |
 NGAL-based |  |  |  |  | 0.350 |
  No | 3 | 1213 | 0.30 (− 0.89 to 1.49) | 0 |  |
  Yes | 3 | 449 | − 1.20 (− 4.12 to 1.72) | 0 |  |
 Emergent need for RRT |  |  |  |  | 0.470 |
  Included | 1 | 106 | − 2.00 (− 7.78 to 3.78) | 0 |  |
  Excluded | 5 | 1556 | 0.17 (− 0.95 to 1.29) | 0 |  |
MV days | Â | Â | Â | Â | Â |
 Population |  |  |  |  | 0.054 |
  Medical | 1 | 488 | 1.00 (− 1.63 to 3.63) | 0 |  |
  Surgical | 1 | 231 | − 2.31 (− 4.50 to − 0.13) | 0 |  |
  Mixed | 4 | 883 | − 7.14 (− 15.05 to 0.76) | 89 |  |
 NGAL-based |  |  |  |  | 0.101 |
  No | 3 | 1213 | − 0.28 (− 2.01 to 1.45) | 0 |  |
  Yes | 3 | 389 | − 9.44 (− 20.25 to 1.38) | 92.2 |  |
 Emergent need for RRT |  |  |  |  | 0.269 |
  Included | 2 | 146 | − 13.28 (− 34.83 to 8.28) | 94.6 |  |
  Excluded | 4 | 1456 | − 1.09 (− 2.78 to 0.60) | 29.7 |  |
RRT days | Â | Â | Â | Â | Â |
 Population |  |  |  |  | 0.001 |
  Medical | 1 | 488 | 2.00 (1.21 to 2.79) | 0 |  |
  Surgical | 1 | 231 | − 16.00 (− 28.57 to − 3.43) | 0 |  |
  Mixed | 4 | 985 | − 5.19 (− 11.25 to 0.86) | 93 |  |
 NGAL-based |  |  |  |  | 0.031# |
  No | 3 | 1315 | 1.46 (0.21 to 2.71) | 60.4 |  |
  Yes | 3 | 389 | − 14.38 (− 28.74 to − 0.02) | 88.1 |  |
 Emergent need for RRT |  |  |  |  | < 0.001 |
  Included | 1 | 40 | − 24.50 (− 32.84 to − 16.16) | 0 |  |
  Excluded | 5 | 1664 | 0.45 (− 1.47 to 2.37) | 74.5 |  |