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Table 2 Haemodynamic and respiratory variables

From: Transpulmonary thermodilution detects rapid and reversible increases in lung water induced by positive end-expiratory pressure in acute respiratory distress syndrome

Variables

High-PEEPstart

Low-PEEP15′

Low-PEEP45′

High-PEEPend

Heart rate (min−1)

89 ± 18

90 ± 19

91 ± 19

91 ± 19

Systolic arterial pressure (mmHg)

130 ± 25

132 ± 19

129 ± 19

124 ± 17

Diastolic arterial pressure (mmHg)

65 ± 20

63 ± 10

62 ± 11

62 ± 10

Mean arterial pressure (mmHg)

86 ± 16

86 ± 13

85 ± 14

83 ± 11

Central venous pressure (mmHg)

15 ± 4

12 ± 4*

12 ± 4*

15 ± 4**

Cardiac index (L/min/m2)

2.77 ± 0.79

3.08 ± 0.85*

3.12 ± 0.90*

2.81 ± 0.89**

Cardiac function index (min−1)

4.0 ± 1.2

4.3 ± 1.3*

4.3 ± 1.3*

4.1 ± 1.3**

Global end-diastolic volume indexed (mL/m2)

750 ± 116

787 ± 168*

791 ± 150*

748 ± 127**

Extravascular lung water (mL/kg)

20 ± 4

18 ± 4*

18 ± 4*

20 ± 5**

Pulmonary vascular permeability index

3.6 ± 1.0

3.5 ± 1.0*

3.5 ± 1.0*

3.6 ± 0.9

Pulse pressure variation (%)

7 [4–14]

6 [4–12]

8 [4–12]

7 [5–11]

Stroke volume variation (%)

8 [5–13]

7 [4–13]

7 [5–13]

8 [6–13]

PEEP (cmH2O)

14 ± 2

5 ± 0*

5 ± 0*

14 ± 2**

Pplateau (cmH2O)

28 ± 2

20 ± 3*

20 ± 3*

28 ± 2**

Respiratory system compliance (mL/cmH2O)

27 [22–32]

26 [24–28]

25 [23–28]

27 [23–31]

SpO2 (%)

98 ± 2

96 ± 3*

95 ± 4*

98 ± 2**

SaO2 (%)

97 ± 3

94 ± 5*

93 ± 6+*

96 ± 4**

PaO2/FiO2 ratio

184 ± 76

150 ± 69*

147 ± 68*

178 ± 76**

  1. FiO2 inspired oxygen fraction, PEEP positive end-expiratory pressure, Pplateau plateau pressure, PaO2 arterial oxygen partial pressure, SaO2 arterial oxygen saturation, SpO2 pulse oxygen saturation
  2. *p < 0.05 vs. High-PEEPstart, **p < 0.05 vs. Low-PEEP45′. See Additional file 2: Table S2 for post hoc comparisons