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Table 2 Haemodynamic and respiratory variables

From: Transpulmonary thermodilution detects rapid and reversible increases in lung water induced by positive end-expiratory pressure in acute respiratory distress syndrome

VariablesHigh-PEEPstartLow-PEEP15′Low-PEEP45′High-PEEPend
Heart rate (min−1)89 ± 1890 ± 1991 ± 1991 ± 19
Systolic arterial pressure (mmHg)130 ± 25132 ± 19129 ± 19124 ± 17
Diastolic arterial pressure (mmHg)65 ± 2063 ± 1062 ± 1162 ± 10
Mean arterial pressure (mmHg)86 ± 1686 ± 1385 ± 1483 ± 11
Central venous pressure (mmHg)15 ± 412 ± 4*12 ± 4*15 ± 4**
Cardiac index (L/min/m2)2.77 ± 0.793.08 ± 0.85*3.12 ± 0.90*2.81 ± 0.89**
Cardiac function index (min−1)4.0 ± 1.24.3 ± 1.3*4.3 ± 1.3*4.1 ± 1.3**
Global end-diastolic volume indexed (mL/m2)750 ± 116787 ± 168*791 ± 150*748 ± 127**
Extravascular lung water (mL/kg)20 ± 418 ± 4*18 ± 4*20 ± 5**
Pulmonary vascular permeability index3.6 ± 1.03.5 ± 1.0*3.5 ± 1.0*3.6 ± 0.9
Pulse pressure variation (%)7 [4–14]6 [4–12]8 [4–12]7 [5–11]
Stroke volume variation (%)8 [5–13]7 [4–13]7 [5–13]8 [6–13]
PEEP (cmH2O)14 ± 25 ± 0*5 ± 0*14 ± 2**
Pplateau (cmH2O)28 ± 220 ± 3*20 ± 3*28 ± 2**
Respiratory system compliance (mL/cmH2O)27 [22–32]26 [24–28]25 [23–28]27 [23–31]
SpO2 (%)98 ± 296 ± 3*95 ± 4*98 ± 2**
SaO2 (%)97 ± 394 ± 5*93 ± 6+*96 ± 4**
PaO2/FiO2 ratio184 ± 76150 ± 69*147 ± 68*178 ± 76**
  1. FiO2 inspired oxygen fraction, PEEP positive end-expiratory pressure, Pplateau plateau pressure, PaO2 arterial oxygen partial pressure, SaO2 arterial oxygen saturation, SpO2 pulse oxygen saturation
  2. *p < 0.05 vs. High-PEEPstart, **p < 0.05 vs. Low-PEEP45′. See Additional file 2: Table S2 for post hoc comparisons