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Table 1 Characteristics of the patients and IHD sessions

From: Comparison between regional citrate anticoagulation and heparin for intermittent hemodialysis in ICU patients: a propensity score-matched cohort study

Variables Before inverse probability of treatment weighting After inverse probability of treatment weighting
RCA group Heparin group p-value RCA group Heparin group p-value |d|
Patients, n 40 35   38 34   
Male gender, n (%) 26 (65) 26 (74) 0.38 (66) (73) 0.60 0.141
Age, years 66 ± 16 69 ± 14 0.36 67 ± 16 67 ± 16 0.97 0.013
Weight at ICU admission, kg 78.7 ± 20.2 78.9 ± 16.4 0.88 81.7 ± 19.8 76.9 ± 15.0 0.25 0.27
BMI at ICU admission, kg/m2 27.6 ± 6.4 28.1 ± 6.3 0.72 28.5 ± 6.3 27.1 ± 5.6 0.32 0.23
SAPS II at ICU admission, points 65 ± 22 62 ± 20 0.62 61 ± 21 63 ± 22 0.81 0.066
Sepsis in ICU stay, n(%) 26 (65) 24 (69) 0.74 (68) (75) 0.56 0.151
Chronic dialysis patients, n(%) 9 (22.5) 9 (26) 0.75 (20.4) (35) 0.26 0.329
IHD sessions, n 124 84   112 82   
Vascular access for IHD, n(%)       0.98  
 Arteriovenous fistula 3 (2.4) 11 (13.1) 0.004 (6.8) (6.9)   0.005
 Temporary central femoral catheter 65 (52.4) 33 (39.3) 0.07 (48.4) (44.7)   0.073
 Temporary central right jugular catheter 37 (29.9) 16 (19) 0.10 (24.0) (27.8)   0.085
 Temporary central left jugular catheter 2 (1.6) 1 (1.2) 1 (1.9) (1.4)   0.040
 Tunneled central venous access 17 (13.7) 23 (27.4) 0.02 (18.9) (19.2)   0.005
Urea volume distribution, L 36.9 ± 6.2 39.1 ± 6.2 0.17 37.5 ± 6.3 38.7 ± 6.3 0.23 0.197
Sodium concentration of the dialysate, mmol/L 139 ± 2 139 ± 2 0.99 139 ± 2 139 ± 2 0.58 0.087
Bicarbonate concentration of the dialysate, mmol/L 33 ± 3 34 ± 2 0.13 33 ± 3 34 ± 2 0.10 0.247
Dialysate with calcium concentration of 1.50 mmol/L, n(%) 87 (70.2) 77 (91.7) 0.001 (70.4) (89.6) 0.008 0.495
Dialysis membrane surface are of 2.1m2, n (%) 106 (85.5) 65 (77.4) 0.064 (86.3) (70.8) 0.01 0.386
Systemic anticoagulation for an indication other than IHD, n(%) 33 (26.6) 30 (35.7) 0.04 (33.7) (39.2) 0.50 0.113
Contraindication to heparin anticoagulation, n(%) 16 (13) 0 (0) 0.001 (13) (0) 0.001 0.537
Invasive mechanical ventilation during IHD, n (%) 46 (37) 33 (39) 0.21 (36) (41) 0.48 0.113
Vasopressor amine infusion during IHD, n (%) 39 (31) 36 (43) 0.006 (29) (42) 0.06 0.289
  1. RCA, regional citrate anticoagulation, BMI, body mass index, SAPS, simplified acute physiology score, IHD, intermittent hemodialysis