Univariate | Multivariate | |||||
---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | |
Gender (reference: male) | 0.82 | 0.56–1.19 | 0.292 | – | – | – |
Admission SOFA Score (per 1 pt increment) | 1.00 | 0.95–1.06 | 0.895 | – | – | – |
Admission SAPS2 Score (per 1 pt increment) | 1.02 | 1.0–1.03 | 0.009 | 1.01 | 1.00–1.03 | 0.129 |
Primary ICU diagnosis (reference septic shock) | ||||||
Non-septic shock | 2.82 | 1.05–7.58 | 0.040 | 4.60 | 1.12–18.79 | 0.034 |
Resuscitated cardiac arrest | 2.18 | 0.84–5.66 | 0.108 | 5.82 | 1.63–20.83 | 0.007 |
Acute on chronic respiratory failure | 1.90 | 0.85–4.23 | 0.116 | 3.85 | 1.09–13.60 | 0.037 |
Acute respiratory failure | 1.40 | 0.67–2.92 | 0.377 | 3.46 | 1.08–11.14 | 0.037 |
Acute kidney injury/metabolic disorders | 1.89 | 0.51–7.00 | 0.338 | 4.99 | 1.00–24.93 | 0.050 |
Neurological disorder | 2.84 | 1.24–6.49 | 0.013 | 6.70 | 2.01–22.33 | 0.002 |
Post-surgery | 1.82 | 0.68–4.88 | 0.236 | 5.80 | 1.39–24.25 | 0.016 |
Other | 1.38 | 0.55–3.48 | 0.493 | 4.97 | 1.40–17.69 | 0.013 |
Invasive mechanical ventilation | 1.23 | 0.79–1.92 | 0.351 | – | – | – |
Length of mechanical ≥ 3 days (reference < 3 days) | 1.62 | 1.06–2.47 | 0.025 | 1.86 | 1.06–3.26 | 0.031 |
Length of RRT (reference no RRT) | ||||||
< 3 days | 0.46 | 0.11–1.86 | 0.275 | 0.77 | 0.17–3.52 | 0.739 |
≥ 3 days | 2.40 | 1.25–4.61 | 0.008 | 2.34 | 0.77–7.13 | 0.135 |
Length of vasopressor requirement (reference no vasopressor) | ||||||
< 3 days | 0.89 | 0.56–1.43 | 0.640 | – | – | – |
≥ 3 days | 1.26 | 0.78–2.03 | 0.352 | – | – | – |
CIRS for geriatrics (per 1 pt increment) | 1.03 | 0.99–1.08 | 0.146 | 1.01 | 0.95–1.07 | 0.747 |
CIRS for geriatrics < 8 | 1.20 | 0.82–1.77 | 0.344 | – | – | – |
Residential living (reference chronic care facility) | ||||||
Supervised residence setting | 0.20 | 0.02–1.58 | 0.126 | 0.09 | 0.01–0.86 | 0.036 |
At home | 0.16 | 0.02–1.15 | 0.068 | 0.10 | 0.01–0.88 | 0.038 |
IADL (per 1 pt increment) | 0.77 | 0.66–0.90 | 0.001 | – | – | – |
IADL ≥ 4 | 0.52 | 0.34–0.79 | 0.002 | 0.75 | 0.41–1.36 | 0.339 |
Katz-ADL (per 1 pt increment) | 0.78 | 0.69–0.89 | < 0.001 | – | – | – |
Katz-ADL ≥ 5 | 0.41 | 0.28–0.61 | < 0.001 | 0.53 | 0.30–0.96 | 0.038 |
History of fall (reference: no) | ||||||
Yes | 1.02 | 0.69–1.5 | 0.924 | – | – | – |
Unknown | 2.19 | 0.30–15.83 | 0.438 | – | – | – |
Cognitive impairment | 1.14 | 0.76–1.72 | 0.526 | – | – | – |
Perceived quality of life (unhappy, very unhappy) | 1.59 | 1.03–2.45 | 0.036 | 1.11 | 0.62–1.98 | 0.723 |
Chronic pain (reference: no) | ||||||
Mild | 0.89 | 0.50–1.59 | 0.699 | – | – | – |
Moderate | 1.34 | 0.82–2.18 | 0.236 | – | – | – |
Severe | 1.10 | 0.63–1.92 | 0.733 | – | – | – |
Presence of anxiety | 1.17 | 0.79–1.75 | 0.431 | – | – | – |
Presence of depressive symptoms | 1.32 | 0.89–1.96 | 0.164 | 0.90 | 0.52–1.55 | 0.698 |
Mini-Zarit (per 1 pt increment) | 1.24 | 1.09–1.41 | 0.001 | – | – | – |
< 2 | 1.71 | 1.14–2.58 | 0.010 | 1.13 | 0.64–1.99 | 0.664 |
Frailty (reference: robust) | ||||||
Prefrail | 1.28 | 0.74–2.22 | 0.377 | 0.96 | 0.50–1.85 | 0.903 |
Frail | 2.41 | 1.42–4.06 | 0.001 | 1.51 | 0.75–3.05 | 0.244 |