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Table 3 Summary of consensus among experts and the degree of recommendations

From: Current use of inotropes in circulatory shock

 

Degree of consensus

Grade of recommendation

Inotrope indications

 1. Inotropes are indicated in septic shock

Good

Strong

 2. Inotropes are indicated in cardiogenic shock

Excellent

Strong

 3. Inotropes are NOT indicated in hypovolemic shock

Excellent

Strong

Choice of inotrope

 4. Dobutamine is the first-line inotrope

Good

Strong

 5. Dopamine is NOT a recommended inotrope

Excellent

Strong

Triggers

 6. Low cardiac output is a trigger for inotropic treatment

Excellent

Strong

 7. Signs of hypoperfusion are a trigger for inotropic treatment

Good

Strong

Targets

 8. Low cardiac output is a target for inotropic treatment

Good

Strong

 9. Signs of hypoperfusion are a target for inotropic treatment

Excellent

Strong

Dosing should be lowered or stopped when

 10. Patients experience unacceptable side effects

Excellent

Strong

 11. Patients show clinical improvement

Good

Strong