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Table 2 Median [IQR] SI levels (L/mU/min) comparison for the first 72 h between male and female cohorts using 6-h blocks

From: Insulin sensitivity in critically ill patients: are women more insulin resistant?

Hours

Male cohort SI (× e−4)

female cohort SI (× e−4)

Median SIM−SIF [95% CI] (× e−4)

 

Overall

 0–71

3.1 [1.7 5.5]

2.5 [1.5 4.0]

0.6 [0.5 0.8]a

 × 

Day 1

 0–5

1.5 [0.5 2.7]

1.3 [0.5 2.3]

0.2 [0.0 0.5]

 × 

 6–11

2.2 [1.3 3.7]

1.8 [0.7 3.3]

0.4 [0.1 0.7]

 × 

 12–17

3.1 [1.7 4.8]

2.2 [1.1 4.2]

0.9 [0.5 1.3]a

 × 

 18–23

3.3 [1.8 5.9]

2.4 [1.5 3.9]

0.9 [0.5 1.2]a

 × 

Day 2

 24–29

3.3 [1.8 5.7]

2.8 [1.6 4.0]

0.5 [0.1 1.1]

 × 

 30–35

3.7 [2.1 6.5]

2.7 [1.8 4.6]

1.0 [0.5 1.4]a

 × 

 36–41

3.6 [2.0 6.0]

2.8 [1.7 4.3]

0.8 [0.2 1.4]a

 × 

 42–47

3.6 [2.0 6.0]

2.9 [1.8 4.2]

0.7 [0.2 1.1]a

 × 

Day 3

 48–53

4.0 [2.2 6.8]

2.9 [1.9 4.4]

1.1 [0.6 1.6]a

 × 

 54–59

4.4 [2.4 6.7]

3.2 [1.9 4.8]

1.1 [0.4 1.6]a

 × 

 60–65

3.8 [2.3 6.0]

3.2 [2.1 4.6]

0.6 [0.1 1.0]

 × 

 66–71

3.8 [2.5 5.7]

3.0 [2.4 4.7]

0.8 [0.4 1.2]a

 × 

  1. Equivalence is indicated by ⇔, Non-equivalence is indicated by × . Equivalence is a separate analysis to statistical difference. Hours where the medians are statistically different (95% CI does not cross zero) to P < 0.05 are in italic
  2. aDifference remaining significant after Bonferroni correction (P < 0.004)