Insulin sensitivity in critically ill patients: are women more insulin resistant?

Annals of Intensive Care

Table 3 Median [IQR] %ΔSI (%) levels comparison between male and female cohorts using 6-h blocks

Hours	Male cohort %ΔSI	Female cohort %ΔSI	Median %ΔSIM − %ΔSIF [95% CI]
Overall
0–71	2.2 [− 17.8 21.6]	3.0 [− 14.4 24.9]	− 0.9 [− 2.7 1.0]	⇔
Day 1
0–5	4.5 [− 23.1 61.3]	1.6 [− 34.5 51.1]	8.0 [− 9.7 9.8]	⇔
6–11	7.2 [− 12.7 38.7]	9.9 [− 15.4 42.0]	− 2.8 [− 9.7 4.0]	⇔
12–17	5.4 [− 10.6 27.4]	4.5 [− 16.3 37.6]	0.7 [− 8.3 7.5]	⇔
18–23	2.9 [− 15.5 24.2]	2.4 [− 14.6 25.0]	0.8 [− 4.7 7.1]	⇔
Day 2
24–29	2.5 [− 12.5 22.1]	4.7 [− 13.0 24.9]	− 2.3 [− 6.9 1.4]	⇔
30–35	0.2 [− 15.6 23.7]	5.6 [− 12.0 24.5]	− 5.8 [− 11.0 − 0.7]	⇔
36–41	1.2 [− 11.4 16.2]	0.3 [− 17.0 16.4]	1.1 [− 3.4 6.5]	⇔
42–47	2.0 [− 12.3 19.8]	0.6 [− 11.9 18.2]	1.4 [− 3.7 5.1]	⇔
Day 3
48–53	2.7 [− 8.6 16.3]	0.7 [− 10.8 18.7]	1.6 [− 2.8 5.4]	⇔
54–59	− 0.8 [− 15.0 13.1]	1.3 [− 10.2 18.1]	− 2.3 [− 5.8 1.9]	⇔
60–65	1.3 [− 11.0 17.5]	4.5 [− 10.0 19.6]	− 3.9 [− 8.0 0.3]	⇔
66–71	1.9 [− 9.6 13.6]	1.6 [− 9.0 14.3]	− 0.6 [− 5.3 3.4]	⇔

Equivalence is indicated by ⇔, non-equivalence is indicated by × . Equivalence is a separate analysis to statistical difference. Hours where the medians are statistically different (95% CI does not cross zero) to P < 0.05 are in italic. No blocks were statistically significant after the Bonferroni correction (P < 0.004)