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Table 2 Thrombotic and ischemic complications depending on anticoagulant treatment

From: Higher anticoagulation targets and risk of thrombotic events in severe COVID-19 patients: bi-center cohort study

 

All patients (n = 179)

Prophylactic group (n = 108)

Therapeutic group (n = 71)

Univariable analysis

Multivariable analysis

OR [95% CI]

p

OR [95% CI]

p

Thrombo-embolic complications—n (%)

57 (31.8)

42 (38.9)

15 (21.1)

0.42 [0.20–0.88]

0.01

0.38 [0.14–0.94]

0.04

Pulmonary embolisms – n (%)

25 (14.0)

22 (20.4)

3 (4.2)

0.17 [0.03–0.61]

< 0.01

0.19 [0.03–0.81]

0.04

Deep vein thrombosis—n (%)

11 (6.1)

10 (9.3)

1 (1.4)

0.13 [0–1.39]

0.18

0.13 [0.01–0.89]

0.04

Cerebral ischemic attack—n (%)

6 (3.4)

6 (5.6)

0

0 [0–1.27]

0.09

0.06 [0–0.68]

0.02

RRT filter/thrombosis—n (%)

32 (17.9)

19 (17.6)

13 (16.7)

0.97 [0;41–2.24]

0.94

1.04 [0.34–3.11]

0.95

Nb of RRT filter per day of RRT—median, IQR

3.0 [1.0; 6.8]

3.0 [2.0; 7.0]

2.0 [1.0; 5.0]

/

0.52

/

/

  1. CI confidence interval, IQR interquartile range, OR odds ratio, RRT renal replacement therapy