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Table 3 Mortality rates of patients with eGFR ≥ 30 who received levosimendan versus dobutamine alone

From: Levosimendan use in patients with acute heart failure and reduced ejection fraction with or without severe renal dysfunction in critical cardiac care units: a multi-institution database study

Outcomes

Event (%)

Levosimendan vs. dobutamine

Levosimendan

Dobutamine

HR (95% CI)

P value

Before PSM patient numbers

102

567

  

 In-hospital mortality

13 (12.7)

61 (10.8)

0.80 (0.43–1.51)

0.491

 5-day mortality

3 (2.9)

19 (3.4)

0.87 (0.26–2.94)

0.822

 14-day mortality

7 (6.9)

38 (6.7)

1.004 (0.45–2.25)

0.992

 30-day mortality

13 (12.7)

57 (10.1)

1.23 (0.68–2.25)

0.496

 90-day mortality

20 (19.6)

83 (14.6)

1.31 (0.80–2.13)

0.285

 180-day mortality

22 (21.6)

99 (17.5)

1.20 (0.76–1.91)

0.438

After PSM patient numbers

82

145

  

 In-hospital mortality

9 (11.0)

25 (17.2)

0.37 (0.15–0.92)

0.032

 5-day mortality

2 (2.4)

10 (6.9)

0.34 (0.07–1.60)

0.173

 14-day mortality

5 (6.1)

19 (13.1)

0.44 (0.17–1.14)

0.091

 30-day mortality

10 (12.2)

28 (19.3)

0.59 (0.28–1.23)

0.160

 90-day mortality

16 (19.5)

31 (21.4)

0.85 (0.45–1.60)

0.604

 180-day mortality

18 (22.0)

36 (24.8)

0.82 (0.46–1.46)

0.501

  1. HR hazard ratio, CI confidence interval, PSM propensity score matching