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Table 3 Hemodynamic parameters at baselines, at the Trendelenburg position and after fluid challenge in responders (n = 22) and non-responders (n = 17)

From: Trendelenburg maneuver predicts fluid responsiveness in patients on veno-arterial extracorporeal membrane oxygenation

Variables

Baseline 1

Trendelenburg position

Baseline 2

Fluid challenge

p value

HR, beat/min

105 [90–115]

107 [89–113]

106 [88–113]

106 [87–113]

0.232

 Responders

103 [86–110]

102 [85–112]

104 [85–110]

101 [84–109]

0.051

 Non-responders

112 [93–116]

113 [98–115]

111 [92–104]

111 [98–101]

0.629

CVP, mmHg

13 [11–15]

15 [13–17]b

13 [10–15]

15 [13–17]b

< 0.001

 Responders

12 [10–15]

14 [11–16]b

12 [9–14]

14 [12–17]b

< 0.001

 Non-responders

14 [13–15]

15 [14–17]b

14 [13–15]a

15 [14–17]b

< 0.001

SBP, mmHg

98 [86–107]

107 [101–115]b

98 [89–106]

111 [105–120]b

< 0.001

 Responders

97 [85–109]

108 [102–115]b

98 [87–107]

116 [109–123]b

< 0.001

 Non-responders

98 [87–105]

105 [99–111]b

98 [90–102]

105[94–111] a, b

< 0.001

DBP, mmHg

59 [51–68]

63 [56–72]b

60 [53–68]

64 [58–72]b

< 0.001

 Responders

56 [48–67]

62 [54–71]b

58 [48–68]

63 [60–72]b

< 0.001

 Non-responders

60 [54–68]

63 [57–72]b

60 [55–68]

66 [57–71]b

< 0.001

PP, mmHg

37 [31–45]

44 [38–48]b

39 [31–45]

46 [38–55]b

< 0.001

 Responders

41 [36–47]

46 [40–51]b

40 [32–47]

51 [46–57]b

< 0.001

 Non-responders

36 [26–43]

38 [32–45]a

36 [30–42]

38 [30–45]a

0.035

VTI, cm

11.5 [9.4–13.3]

12.9 [11.0–14.6]b

11.9 [9.1–13.7]

13.7 [11.5–15.6]b

< 0.001

 Responders

11.8 [8.8–13]

13.5 [10.4–15.5]b

11.7 [9.0–13.1]

14.0 [12.2–16.4]b

< 0.001

 Non-responders

11.5 [11.1–13.7]

12.4 [11.1–13.4]

12.2 [11.0–13.8]

12.4 [11.5–14.0]

0.008

  1. Values are median [IQR]
  2. HR heart rate, SBP systolic blood pressure, DBP diastolic blood pressure, CVP central venous pressure, PP pulse pressure, VTI velocity–time integral
  3. ap < 0.05, comparison between responders (n = 22) and non-responders (n = 17)
  4. bp < 0.05, comparison between Trendelenburg position and baseline 1 or fluid challenge and baseline 2