Skip to main content
Annals of Intensive Care

Table 4 Predictive parameters of receiver operating characteristic (ROC) curves of variable percent changes induced by Trendelenburg position

From: Trendelenburg maneuver predicts fluid responsiveness in patients on veno-arterial extracorporeal membrane oxygenation

Parameters

ΔVTI

ΔPP

ΔSBP

ΔDBP

AUROC

0.93 (0.81–0.98)

0.69 (0.48–0.82)

0.76 (0.56–0.87)

0.73 (0.52–0.85)

Youden index

0.70

0.37

0.49

0.39

Best threshold

10%

10%

13%

6%

Gray zone

6–12%

2–23%

6–14%

2–13%

Values in gray zone

32%

62%

51%

62%

Sensitivity

82 (60–95)

73 (50–89)

55 (32–76)

68 (45–86)

Specificity

88 (64–99)

65 (38–86)

94 (71–100)

71 (44–90)

PPV

90 (68–99)

73 (50–89)

92 (64–100)

75 (51–91)

NPV

79 (54–94)

65 (38–86)

62 (41–80)

63 (38–84)

  1. Values are median true value (95% confidence interval). Best threshold value was determined using the Youden index
  2. The AUROC of ΔVTI was higher than ΔPP (p = 0.004), ΔSBP (p = 0.025) and ΔDBP (p = 0.018). There were no statistical differences among AUROCs of ΔPP, ΔSBP and ΔDBP (ΔPP vs. ΔSBP, p = 0.285; ΔPP vs. ΔDBP, p = 0.760; ΔSBP vs. ΔDBP, p = 0.645)
  3. AUROC area under the receiver operating characteristic curve, PPV positive predictive value, NPV negative predictive value, SBP systolic blood pressure, DBP diastolic blood pressure, PP pulse pressure, VTI velocity–time integral, Δ value indicate percent change of each variable
Back to article page