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Table 3 Discriminative performance

From: Non-invasive method to detect high respiratory effort and transpulmonary driving pressures in COVID-19 patients during mechanical ventilation

Parameter

Threshold measured value

Threshold computed value for excessive value

Area under receiver operating characteristic curve (95% CI)

Sensitivity (95% CI)

Specificity (95% CI)

Excessive dynamic lung stress

PL > 20 cmH2O

Computed ∆PL > 18 cmH2O

1.00 (1.00–1.00)

100% (72–100%)

50% (1–99%)

Computed ∆PL > 19 cmH2O

100% (72–100%)

100% (16–100%)

Computed ∆PL > 20 cmH2O

91% (59–100%)

100% (16–100%)

Excessive respiratory effort

Pmus > 10 cmH2O

Computed Pmus > 8 cmH2O

0.94 (0.81–1.00)

100% (66–100%)

75% (19–99%)

Computed Pmus > 9 cmH2O

78% (40–100%)

75% (19–99%)

Computed Pmus > 10 cmH2O

78% (40–97%)

100% (40–100%)

Pmus > 15 cmH2O

Computed Pmus > 13 cmH2O

0.98 (0.90–1.00)

100% (54–100%)

86% (42–100%)

Computed Pmus > 14 cmH2O

83% (36–100%)

100% (59–100%)

Computed Pmus > 15 cmH2O

83% (36–100%)

100% (59–100%)

  1. ∆PL dynamic transpulmonary driving pressure, Pmus respiratory muscle pressure