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Table 1 Baseline characteristics between the two groups

From: Early combination of albumin with crystalloids administration might be beneficial for the survival of septic patients: a retrospective analysis from MIMIC-IV database

Variables

Total population

(n = 7517)

Crystalloids alone

(n = 6597)

Early combination

(n = 920)

P

Age (yr)

66.75 (16.24)

67.02 (16.62)

67.11 (14.05)

0.852

Female (%)

3651 (48.57)

3253 (49.31)

398 (43.26)

 < 0.001

White (%)

5359 (64.82)

4252 (64.45)

646 (70.22)

 < 0.001

Heartrate (bpm)

89.98 (16.99)

89.83 (16.99)

89.39 (17.04)

0.463

MAP (mmHg)

78.14 (10.50)

78.96 (10.78)

74.10 (8.01)

 < 0.001

Respiratory rate (bpm)

20.39 (4.21)

20.54 (4.21)

19.36 (3.93)

 < 0.001

Temperature (°C)

36.91 (0.66)

36.93 (0.66)

36.81 (0.65)

 < 0.001

SpO2 (%)

96.80 (2.73)

96.72 (2.78)

97.21 (2.46)

 < 0.001

Urine output (L)

1.59 (1.23)

1.64 (1.27)

1.42 (1.04)

 < 0.001

SAPS II score

35.45 (13.54)

34.98 (13.51)

36.88 (13.97)

 < 0.001

SOFA score

4.85 (2.98)

4.64 (2.93)

5.74 (2.92)

 < 0.001

Lactate (mmol/l)

2.63 (2.15)

2.50 (2.09)

2.99 (2.21)

 < 0.001

Weight (kgs)

81.29 (25.66)

80.42 (25.82)

85.11 (22.70)

 < 0.001

Ventilation (%)

3552 (47.25)

2893 (43.85)

659 (71.63)

 < 0.001

RRT (%)

450 (5.99)

397 (6.02)

53 (5.76)

0.758

Vasopressor (%)

4119 (54.80)

3333 (50.52)

786 (85.43)

 < 0.001

Admission, emergency (%)

4753 (63.23)

4363 (66.14)

390 (42.39)

 < 0.001

Insurance (%)

3691 (50.73)

3269 (51.09)

422 (48.06)

0.050

AKI stage (%)

   

 < 0.001

 3

2408 (32.03)

2002 (30.35)

406 (44.13)

 

 2

2472 (32.89)

2127 (32.24)

345 (37.50)

 

 1

1008 (13.41)

902 (13.67)

106 (11.52)

 

 0

1629 (21.67)

1566 (23.74)

63 (6.85)

 

Infection site, blood (%)

2330 (31.00)

2132 (32.32)

198 (21.52)

 < 0.001

Septic shock (%)

2052 (27.30)

1828 (27.71)

224 (24.35)

0.032

Cancer (%)

1022 (13.60)

928 (14.07)

94 (10.22)

0.001

Renal disease (%)

1614 (21.47)

1426 (21.62)

188 (20.43)

0.414

Diabetes (%)

2250 (29.93)

1976 (29.95)

274 (29.78)

0.916

MI (%)

1139 (15.15)

964 (14.61)

175 (19.02)

 < 0.001

Cirrhosis (%)

580 (7.72)

479 (7.26)

101 (10.98)

 < 0.001

Antibiotic

    

Carbapenems (%)

1095 (16.53)

938 (16.07)

157 (19.90)

0.007

Glycopeptide (%)

5785 (87.31)

5030 (86.17)

755 (95.69)

 < 0.001

β-lactams (%)

1875 (28.30)

1754 (30.05)

121 (15.34)

 < 0.001

Aminoglycosides (%)

147 (2.22)

124 (2.12)

23 (2.92)

0.157

  1. MAP mean arterial blood pressure, SAPS II Simplified Acute Physiology Score II, SOFA sequential organ failure assessment, RRT renal replacement therapy, AKI acute kidney injury, MI myocardial infarction