Fig. 5

Comparison of average clock gene expression of the 7 common clock genes in septic shock patients and BOTI subjects. The log₂ gene expression average across time points for each septic shock patient (N = 17) in the septic shock patients and healthy young men (N = 12) from the BOTI study. P-values for the significance of the difference are based on the non-parametric Wilcoxon rank-sum test. ****p < 0.0001, ***p < 0.001, n.s. p > 0.05