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Table 1 Patient characteristics and secondary outcome parameters

From: Circadian rhythms in septic shock patients

Parameter Value (N = 17)
Age (years) 66 (51.5–74)
Male sex, n (%) 7 (41.2)
BMI (kg/m2) 27.7 (23.6–33.4)
TISS-28 42 (37–49.5)
CCI 6 (5–8)
SOFA 17 (11.5–17.5)
SAPS II 69 (57–79.5)
Hemoglobin (g/dL) 8.6 (7.9–10)
Leukocytes (/nL) 14.8 (8.7–19.5)
INR 1.31 (1,27–1.53)
Thrombocytes (/nL) 104 (65–218)
mHLA-DR (antigens/cell)a 5632 (3322–10,192)
Lactate (mg/dL) 15 (12–42.5)
PTT (sec) 40.6 (37.5–57.9)
Hemodialysis, n (%) 14 (82.4)
ECMO, n (%) 3 (17.6)
Ventilation n (%) 17 (100)
Time of mechanical ventilation (hours) 471 (331–910)
ICU length of stay (days) 25 (15.5–40)
Hospital length of stay (days) 29 (15.5–42.5)
In-hospital mortality, n (%) 7 (41.2)
  1. Values at the first point of clock genes measurement, continuous quantities in median with quartiles
  2. BMI body mass index, CCI Charlson Comorbidity Index, ECMO extracorporeal membrane oxygenation, ICU intensive care unit, INR International Normalized Ratio, mHLA-DR human leucocyte antigen-D related on monocytes, PTT partial thromboplastin time, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment Score, TISS Therapeutic Intervention Scoring System
  3. amHLA-DR was measured in 14 patients and median 0.5 (− 3.25–0.25) days before inclusion