Outcome of acute kidney injury: how to make a difference?

Annals of Intensive Care

Table 1 Classical and potential endpoint used to evaluate efficacy of AKI procedure

	Classical outcome	Potential outcome
Prevention	AKI prevalence	Real time GFR
	Change of biomarker
Clinical management	ICU death	Time free of RRT
	Dialysis dependency at discharge	AKI as competitive event to death/complicatoin
		Recovery of renal function
		Functional renal reserve
Follow-up	Long-term survival	Measure of GFR
	End-stage kidney disease	Patient-related quality of life
	CKD

AKI acute kidney injury, GFR glomerular filtration rate, ICU intensive care unit, RRT renal replacement therapy, CKD chronic kidney disease