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Table 2 Baseline characteristics of included patients

From: Low bicarbonate replacement fluid normalizes metabolic alkalosis during continuous veno-venous hemofiltration with regional citrate anticoagulation

Patient characteristics
Number of eligible patients 42
Age, median (IQR), year 59.4 (47.9–69.2)
Sex, no. (%)
 Male 27 (64)
 Female 15 (35)
Weight, median (IQR), kg 74.0 (65.0–88.5)
Body mass index, median (IQR), kg/m2 25.6 (21.8–30.8)
Obesity (BMI ≥ 30), no. (%) 11 (27)
Comorbidities, no. (%)
 Diabetes 8 (19)
 Chronic obstructive pulmonary disease 4 (9)
 Immuno-incompetence 13 (31)
 Cardiac failure 8 (19)
 Liver failure 15 (35)
 End-stage renal disease 3 (7)
 Home oxygen/ventilation 1 (2)
Location before ICU admission, no. (%)
 Other hospital ward 19 (45)
 Emergency room 15 (35)
 Other ICU 8 (19)
Reason for ICU admission, no. (%)
 Cardiovascular/respiratory (e.g. cardiogenic, septic-shock) 35 (83)
 Liver failure 7 (16)
Surgical status at ICU admission, no. (%)
 Scheduled surgery 1 (2)
 Emergency surgery 5 (11)
 No surgery 36 (85)
SAPS 3 at ICU admission, median (IQR) 74.0 58.8–84.0
Duration of CVVH therapy, median (IQR), hours 215 (101–398)
 Pre-switch 66 (38–156)
 Post-switch 111 (45–335)
Respiratory status during study period, no. (%)
 Mechanical ventilation during whole study period 20 (48)
 Mechanical ventilation intermittently during study period 12 (29)
 No mechanical ventilation 9 (21)
 Study participation, median (IQR), hours 114 (84–144)
 ICU stay, median (IQR), days 19 (10–29)
 Hospital stay, median (IQR), days 40 (23–63)
Mortality, no./total no. (%)
 ICU 12/42 (28.6)
 Hospital 19/42 (45.2)