Skip to main content
Annals of Intensive Care

Table 2 Adrenal function of patients according to WIND classification

From: Critical illness-related corticosteroid insufficiency during difficult weaning from mechanical ventilation

Variables

Total (n = 76)

WIND classification

p value

Simple (n = 21)

Difficult (n = 33)

Prolonged (n = 22)

T0 (nmol/L)

655 (438–814)

623 (373–833)

690 (391–849)

615 (482–810)

0.84

Tmax (nmol/L)

977 (794–1356)

1055 (896–1317)

1039 (763–1431)

904 (753–1204)

0.36

Δmax (nmol/L)

429 (267–574)

556 (429–678)

408 (287–638)

261 (151–484)

< 0.01

CIRCI

25 (32.9%)

5 (23.8%)

9 (27.3%)

11 (50%)

0.12

Inadequate adrenal reserve

17 (22.4%)

2 (9.5%)

4 (12.1%)

11 (50%)

< 0.01

AI (Huang and Lin definition [8])

10 (13.2%)

0

1 (3.0%)

9 (40.9%)

 < 0.01

  1. Values are expressed as mean (± SD) or median (IQR) as appropriate
  2. T0: baseline plasma cortisol (before short corticotropin test); Tmax: maximal cortisol post-stimulation; Δmax: maximal cortisol response; CIRCI: critical illness-related corticosteroid insufficiency = T0 < 10 μg/dL (276 nmol/L) and/or Δmax < 9 μg/dL (248 nmol/L); inadequate adrenal reserve: Δmax < 9 μg/dL (248 nmol/L); AI: adrenal insufficiency (Huang and Lin definition) = T0 < 25 μg/dL (694 nmol/L) and Δmax < 9 μg/dL (248 nmol/L)
Back to article page