Variable (reference level) | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
SHR | 95% CI | P | SHR | 95% CI | P | |
Age | 0.964 | 0.943–0.986 | 0.002 | 0.971 | 0.946–0.996 | 0.025 |
Sex (male) | 0.679 | 0.305–1.511 | 0.342 |  |  | – |
BMI | 1.011 | 0.959–1.065 | 0.689 |  |  | – |
SOFA score at admission | 0.865 | 0.770–0.970 | 0.013 |  |  | – |
SAPS II score | 0.970 | 0.937–1.004 | 0.076 |  |  | – |
Hypertension (yes) | 0.700 | 0.507–0.967 | 0.031 |  |  | – |
Chronic ischemic heart disease (yes) | 0.468 | 0.146–1.494 | 0.200 |  |  | – |
COPD (oxygen therapy/CPAP) (yes) | 0.845 | 0.208–3.431 | 0.814 |  |  | – |
Chronic kidney disease (yes) | 1.216 | 0.281–5.266 | 0.793 |  |  | – |
Diabetes (yes) | 0.768 | 0.451–1.310 | 0.333 |  |  | – |
Chronic liver disease (MELD > 10) | 1.054 | 0.295–3.765 | 0.936 |  |  | – |
Need for renal replacement therapy (yes) | 0.208 | 0.093–0.466 | 0.001 | 0.244 | 0.113–0.526 |  < 0.001 |
Late onset VAP (yes) | 0.290 | 0.174–0.483 |  < 0.001 | 0.280 | 0.174–0.450 |  < 0.001 |
CRS < 40 ml/cmH2O in the first 5 days | 1.021 | 0.990–1.053 | 0.195 |  |  | – |
Steroid use (yes) | 1.860 | 0.852–4.060 | 0.119 |  |  | – |
PaO2/FiO2 variation after pronationb | 1.370 | 1.187–1.582 |  < 0.001 | 1.563 | 1.329–1.838 |  < 0.001 |
Cardiovascular complications (yes) | 0.180 | 0.0752–0.433 |  < 0.001 | 0.194 | 0.088–0.427 |  < 0.001 |
Neurologic complications (yes) | 0.376 | 0.165–0.856 | 0.020 | 0.296 | 0.110–0.798 | 0.016 |
Digestive complications (yes) | 0.267 | 0.046–1.583 | 0.146 |  |  | – |
Extra-pulmonary infections (yes) | 0.698 | 0.486–1.000 | 0.050 |  |  | – |
DP before prone positioning | 0.971 | 0.890–1.058 | 0.500 |  |  | – |
ARDS PaO2/FiO2 class (severe)a | 1.775 | 1.143–2.755 | 0.011 | 1.738 | 1.116–2.705 | 0.014 |
Infection during ICU stay (yes) | 0.698 | 0.486–1.000 | 0.050 |  |  | – |