Table 1 Patient characteristics and EEG findings with respect to 28-day survival
From: Simplified frontal EEG in adults under veno-arterial extracorporeal membrane oxygenation
Variable | All patients (n = 118) | 28-day survivors (n = 56) | 28-day non-survivors (n = 62) | p value |
|---|---|---|---|---|
At ICU admission | ||||
Age, years | 58 [48; 66] | 54 [40; 61] | 61 [51; 68] | < 0.001 |
Male gender | 80 (67.8%) | 36 (64.3%) | 44 (71%) | 0.554 |
BMI | 25.3 [23.1; 30.2] | 25.1 [23.3; 30.7] | 26 [22.7; 29.7] | 0.757 |
Pre-hospital Rankin score | 1 [0; 2] | 2 [0; 2] | 1 [0; 2] | 0.518 |
Charlson score | 2 [0; 3] | 1 [0; 2.5] | 2 [1; 3] | 0.075 |
SAPS II | 57 [43; 74.5] | 54 [35; 68] | 60 [44.75; 78] | 0.08 |
Pre-ECMO cardiac arrest | 35 (29.7%) | 15 (26.8%) | 20 (32.3%) | 0.55 |
SOFA score at ICU admission | 11 [8; 13] | 10 [8; 13] | 11 [9; 14] | 0.211 |
SOFA score at time of ECMO cannulation | 12 [10; 15] | 12 [9; 13.5] | 13 [11; 15] | 0.05 |
At time of EEG recording | ||||
Temperature, °C | 36.7 [36.2; 37] | 36.8 [36.2; 37.2] | 36.7 [36.2; 37] | 0.359 |
Catecholamine infusion | 107 (90.7%) | 53 (94.6%) | 54 (87.1%) | 0.211 |
Neuromuscular blockade | 25 (21.2%) | 13 (23.2%) | 12 (19.4%) | 0.656 |
Sedation | 106 (89.8%) | 50 (89.3%) | 56 (90.3%) | 0.999 |
Midazolam, mg/h | 5 [2; 5] | 4 [0; 6] | 5 [2.75; 5] | 0.846 |
Morphine, mg/h | 4 [0; 5] | 4 [0; 5] | 4 [0; 5] | 0.474 |
stdEEG findings | ||||
Reactivity | 109 (92.4%) | 54 (96.4%) | 55 (88.7%) | 0.167 |
Continuity | 88 (74.6%) | 49 (87.5%) | 39 (62.9%) | 0.002 |
Background rhythm (Hz) | 6 [6; 7] | 7 [6; 8] | 6 [6; 7] | 0.003 |
Synek score | 2 [2; 5] | 2 [1; 2] | 2 [2; 5] | < 0.001 |
4-frontEEG | ||||
Reactivity | 106 (89.8%) | 53 (94.6%) | 53 (85.5%) | 0.131 |
Continuity | 88 (74.6%) | 50 (89.3%) | 38 (61.3%) | < 0.001 |
Background rhythm (Hz) | 7 [5; 8] | 7 [6; 8] | 6 [5; 7] | 0.012 |
Synek score | 2 [2; 5] | 2 [1; 2] | 3 [2; 5] | < 0.001 |