Table 1 Patient characteristics at the time of emergency department admission and at PICU admission
From: Malignant pertussis in infants: factors associated with mortality in a multicenter cohort study
Non-survivors (n = 9) | Survivors (n = 14) | p | All patients (n = 23) | |
|---|---|---|---|---|
A: At emergency department admission | ||||
Girl, n (%) | 5 (56) | 6 (43) | 0.7 | 11 (48) |
Postmenstrual age, weeks, median [IQR] | 37 [36–39] | 38 [35–40] | 0.6 | 38 [36–40] |
Preterm, n (%) | ||||
< 37 weeks | 2 (22) | 5 (36) | 0.6 | 7 (30) |
< 33 weeks | 0 (0) | 2 (14) | 0.5 | 2 (9) |
Birth weight, kg, median [IQR] | 2.5 [2.3–3.0] | 2.9 [2.6–3.6] | 0.1 | 2.9 [2.5–3.5] |
Age, days, median [IQR] | 31 [20–54] | 57 [32–74] | 0.1 | 41 [28–69] |
Weight, kg, median [IQR] | 3.5[2.9–4.0] | 3.8 [3.1–5.9] | 0.2 | 3.6 [3–4.6] |
Heart rate, bpm, median [IQR] | 176 [164–195] | 169 [155–179] | 0.3 | 170 [161–195] |
Respiratory failure, n (%) | 8 (89) | 12 (86) | 0.6 | 20 (87) |
Sodium level, mmol/l, median [IQR] | 138 [137–139] | 135 [134–138] | 0.1 | 137 [135–139] |
C-reactive protein, mg, median [IQR] | 67 [20–160] | 4 [0–18] | 0.02 | 10 [0–51] |
pH, median [IQR] | 7.25 [7.19–7.32] | 7.32 [7.25–7.35] | 0.1 | 7.29 [7.23–7.33] |
pCO2, kPa, median [IQR] | 8.2 [7.0–10.5] | 7.4 [6.4–8.5] | 0.4 | 7.5 [7.0–9.0] |
WBC count, G/l, median [IQR] | 26 [19–50] | 36 [20–58] | 0.6 | 32 [19–55] |
Neutrophil count, G/l, median [IQR] | 8 [6–14] | 7 [5–13] | 0.6 | 8 [5–13] |
Lymphocyte count, G/l, median [IQR] | 17 [10–30] | 23 [12–39] | 0.5 | 22 [10–37] |
Lymphocyte/neutrophil ratio < 1, n (%) | 1 (11) | 1 (7) | 1 | 2 (9) |
B: At the time of transfer/admission to PICU | ||||
PELOD score, median [IQR] | 11 [10–20] | 10 [1–14] | 0.25 | 11 [1–20] |
Heart rate, bpm, median [IQR] | 193 [181–202] | 179 [171–199] | 0.25 | 185 [174–200] |
Need for emergency intubation before PICU admission, n (%) | 3 (33) | 3 (21) | 0.44 | 6 (26) |
SpO2/FiO2 ratio, median [IQR] | 426 [259–452] | 384 [227–452] | 0.87 | 384 [238–452] |
pH, median [IQR] | 7.29 [7.22–7.35] | 7.31 [7.22–7.36] | 0.51 | 7.30 [7.23–7.36] |
pCO2 kPa, median [IQR] | 7.3 [6.4–9.4] | 7.19 [6.34–8.5] | 0.68 | 7.3 [6.4–9.0] |
Sodium level, mmol/l, median [IQR] | 129 [126–135] | 135 [131–136] | 0.07 | 134 [128–136] |
Lactate, mmol/l, median [IQR] | 2 [2–4] | 2 [1–3] | 0.29 | 2 [1–3] |
WBC count, G/l, median [IQR] | 52 [38–91] | 54 [41–60] | 0.6 | 53 [42–81] |