Table 2 Predictive patient factors associated with Day-90 mortality in critically ill patients older than 70 years old with COVID-19 stratified on the center variable

Age, years

–

–

 70–75

–

–

 75–79

1.32 (1.08–1.60)

–

 80–84

2.09 (1.64–2.68)

–

 85–91

4.09 (2.97–5.65)

–

Clinical Frailty Scale

–

–

 1–3

–

–

 4

2.14 (1.71–2.68)

2.24 (1.63–3.09)

 5–9

2.81 (2.17–3.64)

2.83 (1.96–4.08)

Body mass index, kg/m²

–

 < 25

–

 25–29

0.96 (0.77–1.20)

1.10 (0.83–1.48)

 30–34

0.85 (0.64–1.11)

0.78 (0.55–1.12)

 35–39

0.89 (0.61–1.31)

0.90 (0.53–1.51)

 ≥ 40

1.33 (0.83–2.13)

1.26 (0.72–2.22)

Diabetes

1.43 (1.20–1.71)

1.42 (1.10–1.82)

Hypertension

1.03 (0.87–1.23)

0.87 (0.68–1.12)

Immunodepression

1.31 (0.99–1.74)

0.97 (0.63–1.48)

Time between first signs and ICU admission

 < 4 days

–

–

 4–7 days

0.88 (0.70–1.12)

0.87 (0.63–1.18)

 ≥ 8 days

0.50 (0.40–0.64)

0.61 (0.44–0.84)

SOFA Cardiovascular component ≥3

1.74 (1.47–2.07)

2.13 (1.66–2.74)

SOFA renal component ≥3

1.84 (1.37–2.49)

1.39 (0.94–2.05)

Invasive mechanical ventilation at Day-1

1.66 (1.38–1.99)

–

Renal replacement therapy at Day-1

2.50 (1.67–3.73)

–

ICU admission after March 29^th

0.67 (0.56–0.80)

0.70 (0.55–0.89)

PaO₂/FiO₂ ratio

–

 200 < PaO₂/FiO₂

–

–

 100 < PaO₂/FiO₂ ≤ 200

1.14 (0.90–1.44)

1.28 (0.97–1.69)

 PaO₂/FiO₂ ≤ 100

1.68 (1.30–2.16)

2.35 (1.73–3.19)