Skip to main content

Table 2 Patients outcomes according to treatment with dexamethasone

From: Impact of dexamethasone on the incidence of ventilator-associated pneumonia and blood stream infections in COVID-19 patients requiring invasive mechanical ventilation: a multicenter retrospective study

 

Overall

(n = 151)

DEXA+

(n = 84)

DEXA−

(n = 67)

p value

At least 1 VAP and/or 1 BSI, n (%)

100 (66)

56 (67)

44 (66)

0.59

At least 1 VAP, n (%)

91 (60)

53 (63)

38 (57)

0.43

Second VAP episode, n (%)

34 (23)

22 (26)

12 (18)

0.23

Third VAP episode, n (%)

15 (10)

11 (13)

4 (6)

0.15

At least 1 BSI, n (%)

44 (29)

24 (29)

20 (30)

0.86

Second BSI episode, n (%)

14 (9)

7 (8)

7 (10)

0.66

Third BSI episode, n (%)

3 (2)

1 (1)

2 (3)

0.59

Invasive MV duration before first VAP, days, median (IQR)

6 (3–12)

5 (3–10)

9 (4–15)

0.02

Mortality at D28, n (%)

25 (17)

14 (17)

11 (16)

0.94

Mortality at D60, n (%)

39 (26)

23 (28)

16 (24)

0.57

Hospital mortality, n (%)

46 (32)

28 (35)

18 (27)

0.27

VFD D28, median (IQR)

0 (0–18)

9 (0–21)

0 (0–11)

0.009

VFD D60, median (IQR)

27 (0–49)

37(0–53)

25 (0–43)

0.12

Duration of mechanical ventilation, days, median (IQR)

17 (9–37)

14 (7–39)

24 (12–36)

0.008

ICU length of stay, days, median (IQR)

24 (15–45)

20 (11–44)

32 (17–46)

0.01

Hospital length of stay, days, median (IQR)

31 (20–49)

28 (18–47)

33 (24–53)

0.06

  1. p values in bold were considered statistically significant
  2. Data are presented as median and interquartile range or absolute value and percentage