Table 1 Baseline characteristics

Demographic characteristics

 Age (years)

59 ± 10

 Male n (%)

37 (79)

 BMI at admission (kg/m²)

28.4 ± 5.3

 APACHE II

6 [5–9]

 SOFA

5 [3–6]

 Charlson Comorbidity Index

2 [1–3]

 Clinical Frailty Scale (CFS)

2 [2, 3]

Physiological variables at ICU admission

 PaO₂/FiO₂ admission

126 ± 43

 paCO₂ admission (mmHg)

46 ± 11

 pH admission

7.40 ± 0.09

Treatments delivered in ICU

 NMBA (days)

4 [2–7]

 Vasopressors n (%)

32 (65)

 Prone n (%)

10 (21)

 Corticosteroids n (%)

1 (2)

 CRRT n (%)

3 (6)

 Cumulative fluid balance (ml)

9 ± 322

Initial inpatient stay

 Hospital stay before ICU admission (days)

3 [1–5]

 Invasive Mechanical Ventilation (days)

12 [6–17]

 ICU length of stay (days)

15 [9–19]

 Hospital length of stay (days)

29 [19–35]

 Ventilator free days (day)

16 [11–22]