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Table 2 Hemodynamic data and CRRT settings at inclusion

From: Prevalence and risk factors of hemodynamic instability associated with preload-dependence during continuous renal replacement therapy in a prospective observational cohort of critically ill patients

Variables

Median [IQR] or count (%)

Vasopressor norepinephrine dose (µg kg−1 min−1)

0.54 [0.21–1.41]

Arterial lactate (mmol L−1)

2.9 [1.5–5.0]

Heart rate (min−1)

96 [74–113]

MAP (mmHg)

70 [62–75]

CVP (mmHg)

8 [6–10]

CITD (L min−1 m−2)

2.8 [2.1–3.3]

CIPC (L min−1 m−2)

2.6 [2.1–3.2]

ISVR (dynes s cm−5)

1757 [1277–2224]

EVLWI (mL kg−1 PBW)

11.5 [8.9–15.2]

PVPI

2.2 [1.9–3.0]

GEDVI (mL m−2)

665 [593–843]

GEF (%)

18 [14–24]

PPV (%)

9 [5–14]

SVV (%)

13 [7–20]

Eadyn

0.8 [0.6–1.0]

Preload-dependence assessed by postural test

22 (52%)

Type of CRRT

 CVVH

39 (93%)

 CVVHD

3 (7%)

Ultrafiltration rate (mL kg−1 h−1)a

26 [24–31]

Dialysate rate (mL kg−1 h−1)b

23 [16–27]

CRRT blood flow (mL min−1)

250 [200–250]

Net ultrafiltration rate (mL kg−1 h−1)

0 [0–2.7]

Ultrafiltrate/dialysate temperature (°C)

38 [37–39]

CRRT circuit anticoagulation

 Heparin

39 (93%)

 Citrate

3 (7%)

  1. CRRT continuous renal replacement therapy, CIPC cardiac index assessed by pulse contour analysis, CITD cardiac index assessed by thermodilution, CVP central venous pressure, CVVH continuous veno-venous hemofiltration, CVVHD continuous veno-venous hemodialysis, Eadyn dynamic arterial elastance, EVLWI extravascular lung water index, GEDVI global end-diastolic volume index, GEF global ejection fraction, IQR interquartile range, ISVR indexed systemic vascular resistance, MAP mean arterial pressure, PBW predicted body weight, PPV pulse pressure variation, PVPI pulmonary vascular permeability index, SVV stroke volume variation
  2. aIn patients treated with CVVH
  3. bIn patients treated with CVVHD