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Table 2 Severity of the disease during the first 24 hours of ICU/ICW admission

From: Seasonal burden of severe influenza virus infection in the critically ill patients, using the Assistance Publique-Hôpitaux de Paris clinical data warehouse: a pilot study

Variable All participants
n = 320
Survivors
n = 257
Non-survivors
n = 63
Acute organ failure
 Respiratory failure
  RR > 30/min or mechanical ventilation, n (%) 211 (65.9) 165 (64.0) 46 (73.8)
  PaO2/FiO2 ratio (mmHg), median [IQR] 187 [90–336] 200 [98–350] 142 [73–260]
  ARDS, n (%) 120 (37.7) 82 (32.0) 38 (61.0)
 Shock
  SBP < 90, DBP < 60 or vasopressors, n (%) 116 (36.2) 81 (31.3) 35 (56.0)
 Renal failure
  Renal replacement therapy, n (%) 22 (6.9) 12 (4.7) 10 (15.9)
 Altered mental status (CGS < 14), n (%) 83 (28.2) 66 (27.8) 17 (29.8)
Severity scores
 SAPS II (points), median [IQR] 37 [28–55] 34 [26–48] 59 [40–81]
 SOFA (points), median [IQR] 5 [2–8] 4 [2–7] 8 [4–14]
 Pneumonia Severity Index, median [IQR] 129 [100–160] 122 [96–153] 152 [131–186]
 Risk class, n (%)
  II 35 (7.9) 25 (9.7) 0 (0.0)
  III 33 (10.2) 31 (11.9) 2 (3.3)
  IV 105 (32.8) 92 (35.7) 13 (21.4)
  V 157 (49.1) 110 (42.8) 47 (75.2)
 CURB65, median [IQR] 2 [1–3] 2 [1–3] 3 [2–4]
 Risk class, n (%)    
  0 24 (7.4) 21 (8.2) 3 (4.1)
  1 67 (21.0) 58 (22.6) 9 (14.5)
  2 83 (26.0) 72 (28.1) 11 (17.2)
  3 86 (26.7) 69 (26.8) 17 (26.3)
  4 41 (12.9) 26 (10.0) 15 (15.4)
  5 19 (6.1) 11 (4.3) 8 (8.4)
  1. Components of the severity scores were imputed when missing: RR > 30/min or mechanical ventilation (n = 6), PaO2/FiO2 ratio (n = 96), ARDS (n = 9), shock (n = 6), altered mental status (n = 26), SAPS II (n = 6). Patient counts for these scores were rounded over the 30 imputed datasets
  2. RR respiratory rate, PaO2 partial pressure of oxygen, FiO2 fraction of inspired oxygen, ARDS acute respiratory distress syndrome, SBP/DBP systolic/diastolic blood pressure, CGS Glasgow coma scale, SAPS simplified acute physiology score, SOFA sequential organ failure assessment