Intra-dialytic hypotension following the transition from continuous to intermittent renal replacement therapy

Annals of Intensive Care

Table 1 Candidate definitions of intra-dialytic hypotension during the first intermittent renal replacement therapy (IRRT) session performed in the intensive care unit after discontinuation of continuous renal replacement therapy

	Criteria (at least one)				Incidence within studied sample
	IRRT interruption	Pharmacologic support	Systolic blood pressure	Diastolic blood pressure	Incidence within studied sample
Definition 1	Discontinuation of IRRT for instability	Initiation of new agent or ≥ 50% increase in VIS			28.6%
Definition 1A	Discontinuation of IRRT for instability	Initiation of new agent or ≥ 50% increase in VIS	Nadir of < 90 mmHg or, if starting sBP is < 90, a decrease of ≥ 10 mmHg		43.7%
Definition 1B	Discontinuation of IRRT for instability	Initiation of new agent or ≥ 50% increase in VIS	Nadir of < 90 mmHg or, if starting sBP is < 90, a decrease of ≥ 10 mmHg	Nadir of < 40 mmHg or, if starting dBP is < 40 mmHg. a decrease of ≥ 5 mmHg	46.8%
Definition 2	Discontinuation of IRRT for instability	Initiation of new agent or any increase in VIS			38.1%
Definition 2A	Discontinuation of IRRT for instability	Initiation of new agent or any increase in VIS	Nadir of < 90 mmHg or, if starting sBP is < 90, a decrease of ≥ 10 mmHg		50.2%
Definition 2B	Discontinuation of IRRT for instability	Initiation of new agent or any increase in VIS	Nadir of < 90 mmHg or, if starting sBP is < 90, a decrease of ≥ 10 mmHg	Nadir of < 40 mmHg or, if starting dBP is < 40 mmHg. a decrease of ≥ 5 mmHg	52.8%

dBP diastolic arterial blood pressure, sBP systolic arterial blood pressure, VIS vasoactive-inotropic score