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Table 1 Candidate definitions of intra-dialytic hypotension during the first intermittent renal replacement therapy (IRRT) session performed in the intensive care unit after discontinuation of continuous renal replacement therapy

From: Intra-dialytic hypotension following the transition from continuous to intermittent renal replacement therapy

  Criteria (at least one) Incidence within studied sample
IRRT interruption Pharmacologic support Systolic blood pressure Diastolic blood pressure
Definition 1 Discontinuation of IRRT for instability Initiation of new agent or ≥ 50% increase in VIS    28.6%
Definition 1A Discontinuation of IRRT for instability Initiation of new agent or ≥ 50% increase in VIS Nadir of < 90 mmHg or, if starting sBP is < 90, a decrease of ≥ 10 mmHg   43.7%
Definition 1B Discontinuation of IRRT for instability Initiation of new agent or ≥ 50% increase in VIS Nadir of < 90 mmHg or, if starting sBP is < 90, a decrease of ≥ 10 mmHg Nadir of < 40 mmHg or, if starting dBP is < 40 mmHg. a decrease of ≥ 5 mmHg 46.8%
Definition 2 Discontinuation of IRRT for instability Initiation of new agent or any increase in VIS    38.1%
Definition 2A Discontinuation of IRRT for instability Initiation of new agent or any increase in VIS Nadir of < 90 mmHg or, if starting sBP is < 90, a decrease of ≥ 10 mmHg   50.2%
Definition 2B Discontinuation of IRRT for instability Initiation of new agent or any increase in VIS Nadir of < 90 mmHg or, if starting sBP is < 90, a decrease of ≥ 10 mmHg Nadir of < 40 mmHg or, if starting dBP is < 40 mmHg. a decrease of ≥ 5 mmHg 52.8%
  1. dBP diastolic arterial blood pressure, sBP systolic arterial blood pressure, VIS vasoactive-inotropic score