Diaphragm dysfunction, lung aeration loss and weaning-induced pulmonary oedema in difficult-to-wean patients

Annals of Intensive Care

Table 1 Baseline patient characteristics

	SBT success N = 22	SBT failure N = 31	p
Age, years	61 (50–71)	63 (55–63)	0.638
Female, n (%)	10 (45)	15 (48)	0.999
Body mass index, kg.m⁻²	24 (21–27)	25 (20–30)	0.609
Pre-existing conditions, n (%)
Hypertension	8 (36)	10 (32)	0.776
Chronic left ventricle failure	4 (18)	8 (26)	0.740
COPD	3 (14)	4 (13)	0.999
SAPS 2	57 (47–77)	65 (49–76)	0.493
SOFA	10 (6–11)	10 (7–12)	0.756
Fluid balance over last 24 h, L	− 0.6 (− 1.2–0.7)	− 0.8 (− 1.6–0.7)	0.205
Length of ICU stay, days	5 (2–6)	5 (2–12)	0.570
Duration of mechanical ventilation, days	4 (2–6)	5 (2–11)	0.468
SBT before inclusion, n	1 (1–1)	1 (1–1)	0.113
Main reason for intubation, n (%)
Acute respiratory failure	13 (59)	16 (52)	0.779
Coma	7 (32)	12 (39)	0.772
Shock	1 (5)	1 (3)	0.999
Post-surgery	1 (5)	2 (6)	0.999
Ventilator settings
Pressure support, cmH₂O	10 (7–10)	12 (10–12)	< .001
PEEP, cmH₂O	5 (5–6)	6 (5–6)	0.076
Expired tidal volume, ml.kg⁻¹ IBW	7 (7–9)	7 (6–7)	0.053

SBT, spontaneous breathing trial; COPD, chronic obstructive pulmonary disease; SAPS, Simplified Acute Physiology Score; SOFA Sequential Organ Failure Assessment; ICU, intensive care unit; PEEP, positive end-expiratory pressure; IBW, ideal body weight