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Table 1 Baseline patient characteristics

From: Diaphragm dysfunction, lung aeration loss and weaning-induced pulmonary oedema in difficult-to-wean patients

  SBT success N = 22 SBT failure N = 31 p
Age, years 61 (50–71) 63 (55–63) 0.638
Female, n (%) 10 (45) 15 (48) 0.999
Body mass index, kg.m−2 24 (21–27) 25 (20–30) 0.609
Pre-existing conditions, n (%)
 Hypertension 8 (36) 10 (32) 0.776
 Chronic left ventricle failure 4 (18) 8 (26) 0.740
 COPD 3 (14) 4 (13) 0.999
SAPS 2 57 (47–77) 65 (49–76) 0.493
SOFA 10 (6–11) 10 (7–12) 0.756
Fluid balance over last 24 h, L − 0.6 (− 1.2–0.7) − 0.8 (− 1.6–0.7) 0.205
Length of ICU stay, days 5 (2–6) 5 (2–12) 0.570
Duration of mechanical ventilation, days 4 (2–6) 5 (2–11) 0.468
SBT before inclusion, n 1 (1–1) 1 (1–1) 0.113
Main reason for intubation, n (%)
 Acute respiratory failure 13 (59) 16 (52) 0.779
 Coma 7 (32) 12 (39) 0.772
 Shock 1 (5) 1 (3) 0.999
 Post-surgery 1 (5) 2 (6) 0.999
Ventilator settings
 Pressure support, cmH2O 10 (7–10) 12 (10–12)  < .001
 PEEP, cmH2O 5 (5–6) 6 (5–6) 0.076
 Expired tidal volume, ml.kg−1 IBW 7 (7–9) 7 (6–7) 0.053
  1. SBT, spontaneous breathing trial; COPD, chronic obstructive pulmonary disease; SAPS, Simplified Acute Physiology Score; SOFA Sequential Organ Failure Assessment; ICU, intensive care unit; PEEP, positive end-expiratory pressure; IBW, ideal body weight