Table 1 Demographics, comorbidities, clinical features and quality of life assessment of all necrotizing soft-tissue infection patients included
|  | Available data | All patients n  =  49 |
|---|---|---|
Demographics | ||
 Age, years, median [IQR] | 49 | 60 [53–70] |
 Male gender | 30 (61.2) | |
Comorbidities | ||
 Diabetes mellitus | 49 | 18 (36.7) |
 Immunodeficiency | 12 (24.5) | |
  Cancer | 4 (8.2) | |
  Corticosteroids | 8 (16.3) | |
 Obliterating arteritis of the lower limbs | 6 (12.2) | |
 Chronic kidney disease | 3 (6.1) | |
 Chronic obstructive pulmonary disease | 6 (12.2) | |
 Cardiac disease | 12 (24.5) | |
 Liver cirrhosis | 1 (2.0) | |
 Chronic alcohol consumption | 5 (10.2) | |
 Obesity | 15 (30.6) | |
Clinical characteristics | ||
 ICU admission | 49 | 24 (49.0) |
 SAPS IIa, median [IQR] | 39 | 26 [18–37] |
 SOFA scorea, median [IQR] | 45 | 1 [0–7] |
 Mechanical ventilation | 49 | 11 (22.5) |
 Shockb | 47 | 18 (38.3) |
 Duration of hospital stay, days, median [IQR] | 49 | 21 [12–32] |
 NSTI topography | 49 |  |
  Limbs | 41 (83.7) | |
  Trunk and/or abdomino-perineal | 9 (18.4) | |
 Body surface affected, %; median [IQR] | 42 | 4 [2–4.5] |
 Circumferential infection | 45 | 7 (15.6) |
 Articular skin involvement | 49 | 23 (46.9) |
 Number of surgical debridements, median [IQR] | 49 | 1 [1, 2] |
Quality of life assessment | ||
 Time between discharge and interview, years; median [IQR] | 49 | 1.5 [1.1–2.4] |
 Self-assessed global quality of life, median [IQR] | 49 | 65 [50–80] |
 Functioning level/independence | ||
  ADL, median [IQR] | 48 | 6 [5.5–6] |
  IADL, median [IQR] | 49 | 7 [5–8] |
 Mental health | ||
  HAD-A, median [IQR] | 49 | 5 [3–9] |
  HAD-A  ≥  8 | 14 (28.6) | |
  HAD-D, median [IQR] | 46 | 3 [1–6] |
  HAD-D  ≥  5 | 17 (37.0) | |
  IES-R, median [IQR] | 49 | 9 [5–22] |
  IES-R  ≥  33 | 10 (20.4) | |
 General quality of life outcomes | ||
  Current place of residence | ||
   Sheltered housing | 49 | – |
   Care home | 1 (2.0) | |
   Private home without assistance | 41 (83.7) | |
   Private home with assistance | 7 (14.3) | |
  Sequelae related to NSTI | 31 (63.3) | |
  Amputations | 9 (18.4) | |
  Walking distance | ||
   Not able to walk | 49 | 2 (4.1) |
   < 50 m | 5 (10.2) | |
   50–200 m | 6 (12.2) | |
   200–500 m | 4 (8.2) | |
   > 500 m | 32 (65.3) | |
 Rehospitalizations | 49 | 25 (51.0) |
 Current employment status | ||
  Full-time employment/studies | 49 | 10 (20.4) |
  Part-time employment/studies | 2 (4.1) | |
  Occasional employment | – | |
  Unemployed | 2 (4.1) | |
  Retired | 23 (46.9) | |
  Long-term disability | 12 (24.5) | |
 Change in employment status since illness | 49 | 18 (36.7) |
 Change in family status | 49 | 6 (12.2) |
  In a relationship | 1 (25.0) | |
  Separated | 3 (75.0) | |
  Parenthood | 1 (16.7) | |
 Augmented alcohol consumption | 49 | 1 (2.0) |
 Augmented tobacco consumption | 1 (2.0) | |
 Augmented drug consumption | 0 (0.0) | |