Skip to main content

Table 1 Baseline characteristics by ICU triage decision

From: Outcome of cancer patients considered for intensive care unit admission in two university hospitals in the Netherlands: the danger of delayed ICU admissions and off-hour triage decisions

  Total study population
N = 780
Too well to benefit—No ICU
N = 258
Too well to benefit—Delayed ICU
N = 74
ICU
N = 382
Too sick to benefit
N = 66
p-value
Age 64 [56–70] 63 [54–69] 66 [59–70] 65 [58–72] 63 [56–70] 0.04*
Male 499 (64%) 166 (64.3%) 44 (59.5%) 248 (64.9%) 41 (62.1%) 0.82
Solid malignancy 503 (64.7%) 163 (63.2%) 41 (55.4%) 244 (63.9%) 55 (83.3%) 0.005*
Hematological malignancy 274 (35.3%) 94 (36.4%) 33 (44.6%) 136 (35.6%) 11 (16.7%)
Both 3 (0.4%) 1 (0.4%)   2 ( 0.5%)  
Metastatic solid malignancy 245 (31.4%) 75 (29.1%) 20 (27%) 108 (28.3%) 42 (63.6%) < 0.001*
Cancer recurrence 71 (9.1%) 33 (12.8%) 5 (6.8%) 27 (7.1%) 6 (9.1%) 0.09
Uncontrolled cancer 408 (52.4%) 145 (56.2%) 33 (44.6%)  173 (45.4%) 57 (86.4%) < 0.001*
CCI 4 [2–6] 4 [2–6] 3 [2–6] 4 [2–6] 6 [4–7] < 0.001*
ECOG PS before hospital 1 [1–2] 1 [1–2] 1 [1–1] 1 [0–2] 2 [1–3] < 0.001*
 0 181 (23.2%) 54 (20.9%) 17 (23%) 108 (28.3%) 2 (3%)
 1 298 (38.2%) 93 (36%) 39 (52.7%) 148 (38.7%) 18 (27.3%)
 2 191 (24.5%) 74 (28.7%) 15 (20.3%) 81 (21.2%) 21 (31.8%)
 3 90 (11.5%) 31 (12%) 3 (4.1%)  36 (9.4%) 20 (30.3%)
 4 15 (1.9%) 5 (1.9%) 0 (0%)  6 (1.6%) 4 (6.1%)
 Unknown 5 (0.6%) 1 (0.4%) 0 (0%) 3 (0.8%) 1 (1.5%)
MEWS 5 [3–6] 4 [2–6] 5 [4–7]  5 [4–7] 5 [3–6] < 0.001*
Unknown 80 (10.3%) 14.(5.4%) 4 (5.4%) 54 (14.1%) 8 (12.1%)
Cancer treatment before ICU 684 (88%) 223 (86.8%) 65 (87.8%) 343 (90.3%) 53 (80.3%) 0.12
Unknown 3 (0.4%)     
Immunocompromised 560 (71.8%) 199 (77.1%) 49 (66.2%) 265 (69.4%) 47 (71.2%) 0.13
Year ICU consult      0.20
 2016 214 (27.4%) 67 (26%) 22 (29.7%) 114 (29.8%) 11 (16.7%)  
 2017 204 (26.2%) 62 (24%) 18 (24.3%) 108 (28.3%) 16 (24.2%)
 2018 222 (28.5%) 78 (30.2%) 18 (24.3%) 99 (25.9%) 27 (40.9%)
 2019 140 (17.9%) 51 (19.8%) 16 (21.6%) 61 (16%) 12 (18.2%)
Earlier ICU admission before consult 77 (9.9%) 24 (9.3%) 8 (10.8%) 45 (11.8%) 0 (0%) 0.03*
One ICU physician 318 (40.8%) 109 (42.2%) 35 (47.3%) 158 (41.4%) 16 (24.2%) 0.007*
Two ICU physicians 385 (49.4%) 130 (50.4%) 37 (50%) 176 (46.1%) 42 (63.6%)
More than two ICU physicians 77 (9.9%) 19 (7.4%) 2 (2.7%) 48 (12.6%) 8 (12.1%)
One referring physician (ref) 164 (21.2%) 59 (23%) 19 (26%) 80 (21.2%) 6 (9.1%) < 0.001*
Two referring physicians 496 (64.2%) 175 (68.1%) 41 (56.2%) 240 (63.7%) 40 (60.6%)
More than two referring physicians 113 (14.6%) 23 (8.9%) 13 (17.8%) 57 (15.1%) 20 (30.3%)
Location consult   < 0.001*
 Emergency room (ref) 137 (17.6%) 30 (11.6%) 4 (5.4%) 81 (21.2%) 22 (33.3%)  
 Ward 483 (61.9%) 197 (76.4%) 55 (74.3%) 190 (49.7%) 41 (62.1%)
 Other 160 (20.5%) 31 (12%) 15 (20.3%) 111 (29.1%) 3 (4.5%)
On-hours (ref) 315 (40.4%) 95 (36.8%) 27 (36.5%) 163 (42.7%) 30 (45.5%) 0.34
Off-hours 465(59.6%) 163 (63.2%) 47 (63.5%) 219 (57.3%) 36 (54.5%)
Weekend 244 (31.3%) 77 (29.8%) 25 (33.8%) 118 (30.9%) 24 (36.4%) 0.73
Consult reason
 Shock 150 (19.2%) 30 (11.6%) 5 (6.8%) 103 (27%) 12 (18.2%) < 0.001*
 Respiratory insufficiency 483 (61.9%) 147 (57%) 50 (67.6%) 242 (63.4%) 44 (66.7%) 0.20
 Altered consciousness 139 (17.8%) 36 (14.0%) 7 (9.5%) 80 (20.9%) 16 (24.2%) 0.01*
 Sepsis 214 (27.4%) 47 (18.2%) 22 (29.7%) 135 (35.3%) 10 (15.2%) < 0.001*
 Acute kidney injury 94 (12.1%) 18 (7%) 10 (13.5%)  60 (15.7%) 6 (9.1%) 0.008*
 High MEWS 23 (2.9%) 16 (6.2%) 3 (4.1%) 2 (0.5%) 2 (3%) 0.001*
 Hemodynamic instability 280 (35.9%) 86 (33.3%) 21 (28.4%) 152 (39.8%) 21 (31.8%) 0.14
 Other 99 (12.7%) 42 (16.3%) 9 (12.2%) 36 (9.4%) 12 (18.2%) 0.05
  1. Table shows data of first ICU consultation of the hospital admission
  2. A p-value of < 0.05 is considered significant (marked by an *)
  3. CCI Charlson Comorbidity Index, ECOG PS Eastern Cooperative Oncology Group Performance Status, MEWS Modified Early Warning Score, On-hours during dayshift