Fig. 3

Platelet activation gene expression profile in critically ill patients. a Normalized RNA expression of ITGA2B, GP1BB, PPBP, SELPG depending on severity grade. *p < 0.05, **p < 0.01, ***p < 0.001 (Kruskal–Wallis test followed by Dunn’s post-test). b, c Gene expression correlation with CRP levels (b) or platelet counts (c). r and p values were determined using Spearman’s correlation test. Groups: healthy controls (n = 13), mild-to-moderate (n = 11), severe (n = 10) and critical (n = 11)