Fig. 4

Prediction potential of hemostasis genes for mechanical ventilation. a RNA levels of non-severe patients at admission depending on their future aggravation, normalized to platelet counts. Dashed lines represent optimal threshold obtained by maximization of Youden’s index for significant AUCs. b Associated ROC curves, with area under the curve (AUC) and associated p values. c Bar graphs indicating the number of patients in each group depending on normalized RNA levels of a single gene with respect to the optimal threshold. Groups: no intubation (n = 16) and intubation (n = 5)