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Table 3 Predictors of bleeding occurrence during and after PDT

From: Percutaneous dilatational tracheotomy in high-risk ICU patients

Attribute Univariate analysis Multivariate analysis
OR [95% CI] p-value OR [95% CI] p-value
Age (per year) 1 [0.99, 1.02] 0.61   
Gender 0.75 [0.41, 1.32] 0.34   
Body mass index (per kg/m2) 1.02 [0.98, 1.07] 0.32   
Hypertension 1.45 [0.84, 2.6] 0.19 1.13 [0.63, 2.09] 0.683
Diabetes mellitus 1.01 [0.58, 1.71] 0.97   
Current smoker 0.56 [0.3, 1.01] 0.07 0.54 [0.28, 0.98] 0.051
Chronic kidney disease 2.2 [1.34, 3.62] 0.002 1.75 [1.01, 3.03] 0.047
Previous Stroke 2.35 [1.24, 4.26] 0.01 2.13 [1.1, 3.97] 0.02
Atrial fibrillation 1.08 [0.66, 1.77] 0.76   
Heparin (prophylactic dosage) 0.99 [0.46, 1.93] 0.99   
Heparin (therapeutic dosage) 0.92 [0.47, 1.68] 0.79   
Aspirin and heparin (prophylactic dosage) 0.94 [0.27, 2.43] 0.9   
Aspirin and heparin (therapeutic dosage) 0.86 [0.4, 1.67] 0.68   
P2Y12 receptor and heparin (therapeutic dosage) 1.22 [0.28, 3.65] 0.76   
DAPT with heparin (prophylactic dosage) 1.11 [0.56, 2.04] 0.75   
Triple-therapy 0.93 [0.49, 1.66] 0.82   
Creatinine (per mg/dl) 1.23 [0.97, 1.55] 0.08 1.06 [0.79, 1.38] 0.698
Hemoglobin (per g/dl) 0.92 [0.77, 1.08] 0.32   
Platelet count (per G/l) 0.7 [0.55, 0.88] 0.003 0.73 [0.56, 0.92] 0.009
INR 1.59 [0.8, 2.85] 0.14 0.61 [0.13, 1.75] 0.438
aPTT (per s) 1.01 [0.99, 1.02] 0.32   
  1. Logistic regression models were used to determine important predictors for bleeding during and after PDT. Factors with a P-value < 0.2 in the univariable analyses were included in the multivariable model. P-values < 0.05 were considered significant. OR Odds ratio, 95% CI 95% confidence interval, INR International Normalized Ratio, aPTT activated Partial Thromboplastin Time