Percutaneous dilatational tracheotomy in high-risk ICU patients

Annals of Intensive Care

Table 3 Predictors of bleeding occurrence during and after PDT

Attribute	Univariate analysis		Multivariate analysis
Attribute	OR [95% CI]	p-value	OR [95% CI]	p-value
Age (per year)	1 [0.99, 1.02]	0.61
Gender	0.75 [0.41, 1.32]	0.34
Body mass index (per kg/m²)	1.02 [0.98, 1.07]	0.32
Hypertension	1.45 [0.84, 2.6]	0.19	1.13 [0.63, 2.09]	0.683
Diabetes mellitus	1.01 [0.58, 1.71]	0.97
Current smoker	0.56 [0.3, 1.01]	0.07	0.54 [0.28, 0.98]	0.051
Chronic kidney disease	2.2 [1.34, 3.62]	0.002	1.75 [1.01, 3.03]	0.047
Previous Stroke	2.35 [1.24, 4.26]	0.01	2.13 [1.1, 3.97]	0.02
Atrial fibrillation	1.08 [0.66, 1.77]	0.76
Heparin (prophylactic dosage)	0.99 [0.46, 1.93]	0.99
Heparin (therapeutic dosage)	0.92 [0.47, 1.68]	0.79
Aspirin and heparin (prophylactic dosage)	0.94 [0.27, 2.43]	0.9
Aspirin and heparin (therapeutic dosage)	0.86 [0.4, 1.67]	0.68
P2Y12 receptor and heparin (therapeutic dosage)	1.22 [0.28, 3.65]	0.76
DAPT with heparin (prophylactic dosage)	1.11 [0.56, 2.04]	0.75
Triple-therapy	0.93 [0.49, 1.66]	0.82
Creatinine (per mg/dl)	1.23 [0.97, 1.55]	0.08	1.06 [0.79, 1.38]	0.698
Hemoglobin (per g/dl)	0.92 [0.77, 1.08]	0.32
Platelet count (per G/l)	0.7 [0.55, 0.88]	0.003	0.73 [0.56, 0.92]	0.009
INR	1.59 [0.8, 2.85]	0.14	0.61 [0.13, 1.75]	0.438
aPTT (per s)	1.01 [0.99, 1.02]	0.32

Logistic regression models were used to determine important predictors for bleeding during and after PDT. Factors with a P-value < 0.2 in the univariable analyses were included in the multivariable model. P-values < 0.05 were considered significant. OR Odds ratio, 95% CI 95% confidence interval, INR International Normalized Ratio, aPTT activated Partial Thromboplastin Time