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Table 1 Comparison of baseline characteristics between survivors and non-survivors

From: Novel phenotypes of coronavirus disease: a temperature-based trajectory model

Demographics Survivors (n = 1357) Non-survivors (n = 223) All patients (n = 1580) p
Age (years) 56.2 ± 13.9 67.1 ± 12.4 57.7 ± 14.2  < 0.001
Male [n (%)] 703 (51.8) 136 (60.9) 839 (53.1) 0.011
Comorbidities
 Hypertension [n (%)] 322 (23.7) 75 (33.6) 397 (25.1) 0.002
 Diabetes mellitus [n (%)] 141 (10.3) 43 (19.2) 184 (11.6)  < 0.001
 Chronic heart diseases [n (%)] 77 (5.6) 27 (12.1) 104 (6.5)  < 0.001
 COPD [n (%)] 15 (1.1) 11 (4.9) 26 (1.6)  < 0.001
 Chronic renal diseases [n (%)] 27 (2.0) 7 (3.1) 34 (2.1) 0.273
 Malignant tumor [n (%)] 31 (2.3) 14 (6.2) 45 (2.8)  < 0.001
Laboratory and disease severity indexes
 Initial white blood cell count (10^9/L) 6.6 ± 3.2 10.2 ± 5.2 7.1 ± 3.7  < 0.001
 Maximum white blood cell count (10^9/L) 7.8 ± 3.6 16.5 ± 8.8 9.0 ± 5.6  < 0.001
 Initial neutrophil count (10^9/L) 4.6 ± 2.6 8.3 ± 4.8 5.1 ± 3.3  < 0.001
 Maximum neutrophil count (10^9/L) 5.7 ± 3.3 14.1 ± 8.0 6.9 ± 5.2  < 0.001
 Initial lymphocyte cell count (10^9/L) 1.2 ± 0.6 0.8 ± 0.6 1.1 ± 0.6  < 0.001
 Minimum lymphocyte cell count (10^9/L) 1.0 ± 0.6 0.5 ± 0.4 0.9 ± 0.6  < 0.001
 Initial hemoglobin level (g/dl) 122.6 ± 16.7 119.9 ± 19.1 122.2 ± 17.1 0.025
 Initial platelet count (10 /L) 224 ± 89 166 ± 73 216 ± 89  < 0.001
 Initial albumin level (g/L) 33.9 ± 4.3 30.4 ± 4.2 33.4 ± 4.5  < 0.001
 Initial serum creatinine (mmol/l) 72.1 ± 33.1 96.3 ± 78.6 75.5 ± 43.3  < 0.001
 PaO2/FiO2 283 ± 128 170 ± 146 266 ± 137  < 0.001
 Initial CRP level (mmol/L) 29 ± 35 (n = 30) 84 ± 49 (n = 43) 36 ± 41 (n = 343)  < 0.001
 Maximum CRP level (mmol/L) 38 ± 41 (n = 30) 118 ± 46 (n = 43) 48 ± 49 (n = 343)  < 0.001
 SOFA score on admission [median (IQR)] 1 (0–2) 3 (1–4) 1 (0–2)  < 0.001
 Maximum SOFA score [median (IQR)] 1 (0–2) 6 (4–9) 1 (0–2)  < 0.001
Study center 0.011
 Union Jiangbei Hospital 160 (11.7) 35 (15.6) 195 (12.3)  
 Wuhan No.9 Hospital 138 (10.1) 25 (11.2) 163 (10.3)  
 Wuhan No.4 Hospital 42 (3.1) 11 (4.9) 53 (3.3)  
 Wuhan Jinyintan Hospital 1003 (73.9) 145 (65.0) 1148 (72.6)  
 Huangshi central Hospital 14 (1.0) 7 (3.1) 21 (1.3)  
Immunotherapy
Corticosteroid therapy [n (%)] 300 (22.1) 117 (52.4) 417 (26.3)  < 0.001
Interferon therapy [n (%)] 198 (14.5) 34 (15.2) 232 (13.8) 0.798
Gamma-globulin therapy [n (%)] 270 (19.8) 88 (39.4) 358 (21.3)  < 0.001
Clinical outcomes
 ARDS [n (%)] 180 (13.2) 197 (88.3) 377 (23.8)  < 0.001
 Mechanical ventilation [n (%)] 26 (1.9) 78 (34.9) 104 (6.5)  < 0.001
 Duration of mechanical ventilation (days) 10.3 ± 3.7 5.6 ± 4.6 6.7 ± 4.8  < 0.001
 Hospital length of stay (days) 13.5 ± 7.1 10.5 ± 7.0 13.0 ± 7.1  < 0.001
 ICU admission [n (%)] 164 (12.1) 109 (48.8) 273 (17.2)  < 0.001
 ICU length of stay (days) 10.4 ± 10.3 8.3 ± 7.3 9.6 ± 9.3 0.064
  1. COPD chronic obstructive pulmonary disease, PaO2/FiO2 ratio of partial pressure of arterial oxygen to fraction of inspired oxygen, SOFA Sequential Organ Failure Assessment, ARDS acute respiratory distress syndrome, ICU intensive care unit