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Table 4 Effect estimates of dynamic arterial elastance for predicting the mean arterial pressure response to fluid expansion

From: Predictive performance of dynamic arterial elastance for arterial pressure response to fluid expansion in mechanically ventilated hypotensive adults: a systematic review and meta-analysis of observational studies

Variables Subgroups No. of studies AUHSROC Sensitivity (%) Specificity (%) Diagnostic odds ratio
Primary analysis All studies 8 0.92 (0.89, 0.94) 0.85 (0.71, 0.93) 0.85 (0.69, 0.94) 22.8 (5.5, 93.6)
Classification of patients ICU patients 5 0.96 (0.94, 0.98) 0.92 (0.75, 0.98) 0.92 (0.82, 0.97) 76.3 (13.0, 448.9)
Surgical patients in the operating room 3 0.72 (0.67, 0.75) 0.69 (0.56, 0.80) 0.66 (0.48, 0.81) 4.5 (1.3, 14.9)
Fluid type Colloid 4 0.90 (0.87, 0.93) 0.81 (0.60, 0.92) 0.88 (0.58, 0.98) 19.4 (2.2, 174.1)
Crystalloid 4 0.93 (0.90, 0.95) 0.89 (0.65, 0.97) 0.85 (0.62, 0.95) 30.0 (3.4, 248.7)
Measurement technique Arterial waveform analysis 5 0.92 (0.90, 0.94) 0.85 (0.58, 0.96) 0.87 (0.61, 0.97) 19.1 (2.6, 139.8)
Oesophageal Doppler 2 0.90 (0.87, 0.92) 0.85 (0.66, 0.94) 0.80 (0.49, 0.94) 21.8 (1.0, 458.4)
PICCO 1
Sensitivity analyses Excluding the outlier* 7 0.88 (0.85, 0.91) 0.80 (0.68, 0.89) 0.83 (0.66, 0.92) 15.3 (4.0, 59.2)
Excluding 2 retrospective studies 6 0.94 (0.91, 0.96) 0.88 (0.71, 0.95) 0.87 (0.71, 0.95) 30.1 (6.5, 138.6)
  1. MAP mean arterial pressure, ICU intensive care unit, AUHSROC area under hierarchical summary receiver operating characteristic curve, PICCO pulse indicator continuous cardiac output
  2. * The study by Guarracino et al. was identified as the outlier based on a Galbraith plot