|
Variables
|
Subgroups
|
No. of studies
|
AUHSROC
|
Sensitivity (%)
|
Specificity (%)
|
Diagnostic odds ratio
|
|---|
|
Primary analysis
|
All studies
|
8
|
0.92 (0.89, 0.94)
|
0.85 (0.71, 0.93)
|
0.85 (0.69, 0.94)
|
22.8 (5.5, 93.6)
|
|
Classification of patients
|
ICU patients
|
5
|
0.96 (0.94, 0.98)
|
0.92 (0.75, 0.98)
|
0.92 (0.82, 0.97)
|
76.3 (13.0, 448.9)
|
|
Surgical patients in the operating room
|
3
|
0.72 (0.67, 0.75)
|
0.69 (0.56, 0.80)
|
0.66 (0.48, 0.81)
|
4.5 (1.3, 14.9)
|
|
Fluid type
|
Colloid
|
4
|
0.90 (0.87, 0.93)
|
0.81 (0.60, 0.92)
|
0.88 (0.58, 0.98)
|
19.4 (2.2, 174.1)
|
|
Crystalloid
|
4
|
0.93 (0.90, 0.95)
|
0.89 (0.65, 0.97)
|
0.85 (0.62, 0.95)
|
30.0 (3.4, 248.7)
|
|
Measurement technique
|
Arterial waveform analysis
|
5
|
0.92 (0.90, 0.94)
|
0.85 (0.58, 0.96)
|
0.87 (0.61, 0.97)
|
19.1 (2.6, 139.8)
|
|
Oesophageal Doppler
|
2
|
0.90 (0.87, 0.92)
|
0.85 (0.66, 0.94)
|
0.80 (0.49, 0.94)
|
21.8 (1.0, 458.4)
|
|
PICCO
|
1
|
–
|
–
|
–
|
–
|
|
Sensitivity analyses
|
Excluding the outlier*
|
7
|
0.88 (0.85, 0.91)
|
0.80 (0.68, 0.89)
|
0.83 (0.66, 0.92)
|
15.3 (4.0, 59.2)
|
|
Excluding 2 retrospective studies
|
6
|
0.94 (0.91, 0.96)
|
0.88 (0.71, 0.95)
|
0.87 (0.71, 0.95)
|
30.1 (6.5, 138.6)
|
- MAP mean arterial pressure, ICU intensive care unit, AUHSROC area under hierarchical summary receiver operating characteristic curve, PICCO pulse indicator continuous cardiac output
- * The study by Guarracino et al. was identified as the outlier based on a Galbraith plot
