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Table 2 Case/control comparison after matching

From: Gastrointestinal bleeding in critically ill immunocompromised patients

Characteristics Case group Control group p value
n = 112 % or med [IQR] n = 112 % or med [IQR]
Generalities
 Age 62 [48–70] 60 [50–69] 0.92
 Male gender 85 76% 70 62% 0.042
 BMI 26 [24–29] 24 [21–28] 0.11
Treatments at admission
 Anticoagulants 15 13%   21% 0.88
 Antiplatelet agent 14 12% 16 14% 0.26
 PPI before admission 44 39% 47 42% 0.79
GIB characteristics
 Upper GIB 93 83% 89 79% 0.61
 Melena 66 59% 72 64% 0.49
 Hematochezia 27 24% 37 33% 0.18
 Hematemesis 50 45% 38 34% 0.13
Biology during GIB
 Thrombopenia < 50 G/L 13 19% 41 37% 0.0.18
 Hemoglobin (nadir) (g/dl) 6.4 [5.8–7.2] 6.7 [5.9–7.4] 0.47
 PT (%) 48 [33–75] 70 [57–78.5] < 0.0001
 ACT 1.65 [1.34–2.4] 1.14 [1–1.5] < 0.0001
 Lactatemia (mmol/l) 1.7 [1–3.3] 2.1 [1.2–3.9] 0.22
 Fibrinogen < 1 g/l 15 15% 4 4% 0.008
Organ failure
 Shock 47 42% 48 43% 1.00
 Vasopressive drugs 47 42% 40 36% 0.41
 Renal replacement therapy 27 24% 32 29% 0.54
 Mechanical ventilation 96 86% 86 77% 0.12
 SOFA score during GIB 6 [4–11] 6 [3–12] 0.37
 AIM 65 2 [1–3] 2 [1–3] 0.24
 AIM65 score ≥ 2, n (%) 83 74% 74 66% 0.24
Transfusion
 RBC units 4 [2–7] 5 [2–9] 0.11
 Platelets units 0 [0–0] 5.5 [0–18] < 0.0001
 FFP units 0 [0–2] 0 [0–2] 0.76
Interventional care
 EGD, hemostatic procedure 75 68% 52 46% 0.002
 Colonoscopy 22 20% 31 28% 0.21
 CT angiography 13 12% 20 18% 0.26
 Arterio-embolization 7 6% 7 6% 1.00
 Hemostatic surgery 3 3% 6 5% 0.50
Length of ICU stay, days 4 [2–15] 5 [2–10] 0.085
Length of hospital stay, days 32 [12–58] 29 [13–47] 0.72
  1. BMI: body mass index, ACLF acute-on-chronic liver failure, PPI proton pump inhibitor, ICU intensive care unit, GIB gastrointestinal bleeding, PT prothrombin time, ACT activated coagulation time, SOFA sequential organ failure assessment, RBC red blood cell, FFP fresh frozen plasma, GVH graft versus host, EGD esophagogastroduodenoscopy, CT computed tomography, TIPS transjugular intrahepatic portosystemic shunts