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Table 1 Characteristics of COVID-19 patients admitted in the ICU, according to the French administrative region, March, 1st to May, 31st 2020

From: Case fatality inequalities of critically ill COVID-19 patients according to patient-, hospital- and region-related factors: a French nationwide study

Population 2017 (n) Overall population Auvergne-Rhône-Alpes Bourgogne-Franche-Comté Bretagne Centre-Val de Loire Corse Grand Est
64,639,133 7,949,036 2,810,551 3,318,904 2,577,191 334,938 5,549,586
Patient in ICU—all causes (n) 58,033 6942 2235 2166 1831 202 5500
Critically ill COVID-19 patients in ICU (n, %) 14,513 25.0% 1358 19.6% 580 26.0% 256 11.8% 410 22.4% 44 21.8% 2130 38.7%
Age class (n, %)               
 < 65 y.o 7145 49.2% 521 38.4% 213 36.7% 110 43.0% 182 44.4% 14 31.8% 928 43.6%
 65–79 y.o 6280 43.3% 698 51.4% 299 51.6% 129 50.4% 196 47.8% 25 56.8% 1066 50.0%
 ≥ 80 y.o 1088 7.5% 139 10.2% 68 11.7% 17 6.6% 32 7.8% 5 11.4% 136 6.4%
Age (mean ± s.d.) 63 ± 13 65.9 ± 12.4 66.9 ± 11.5 63.4 ± 13.3 64.2 ± 12.6 67.2 ± 13.2 64.4 ± 11.9
Sex ratio (M/F) 2.5 2.7 2.3   2.4 2.3 2.4 2.6
SAPS II (mean ± s.d.) 39.47 ± 17 38.85 ± 16.1 41.46 ± 15.6 37.69 ± 16.6 37.73 ± 15.9 39.91 ± 15.3 42.09 ± 17.4
Comorbidities (n, %) 11,739 80.9% 1132 83.4% 494 85.2% 196 76.6% 356 86.8% 33 75.0% 1782 83.7%
 High blood pressure 7131 49.1% 695 51.2% 293 50.5% 122 47.7% 229 55.9% 16 36.4% 1158 54.4%
 Chronic heart disease 4971 34.3% 545 40.1% 243 41.9% 84 32.8% 157 38.3% 14 31.8% 893 41.9%
 Diabetes 4487 30.9% 447 32.9% 189 32.6% 73 28.5% 150 36.6% 8 18.2% 667 31.3%
 Obesity 3549 24.5% 328 24.2% 139 24.0% 59 23.0% 129 31.5% 5 11.4% 563 26.4%
 Cancer 3078 21.2% 370 27.2% 174 30.0% 64 25.0% 128 31.2% 14 31.8% 567 26.6%
 Chronic renal disease 2352 16.2% 310 22.8% 93 16.0% 46 18.0% 84 20.5% 4 9.1% 448 21.0%
 Chronic pulmonary disease 1913 13.2% 218 16.1% 96 16.6% 34 13.3% 75 18.3% 6 13.6% 319 15.0%
 Neurological disease 1120 7.7% 166 12.2% 64 11.0% 12 4.7% 33 8.0% 2 4.5% 204 9.6%
 Chronic liver disease 1046 7.2% 102 7.5% 41 7.1% 16 6.3% 35 8.5% 1 2.3% 184 8.6%
ICU specific care supports (n, %)               
 Central venous catheter 7407 51.0% 697 51.3% 258 44.5% 137 53.5% 215 52.4% 25 56.8% 1389 65.2%
 Continuous hemodynamic monitoring 7601 52.4% 774 57.0% 225 38.8% 114 44.5% 238 58.0% 30 68.2% 1319 61.9%
 Vasoactive treatment* 8528 58.8% 772 56.8% 367 63.3% 142 55.5% 230 56.1% 16 36.4% 1438 67.5%
  Renal replacement therapy 2165 14.9% 212 15.6% 64 11.0% 31 12.1% 49 12.0% 3 6.8% 259 12.2%
  ECMO 587 4.0% 25 1.8% 13 2.2% 6 2.3% 13 3.2% 2 4.5% 82 3.8%
Mechanical ventilation** (n, %)               
 Non invasive/high flow oxygenotherapy 6546 45.1% 664 48.9% 241 41.6% 105 41.0% 191 46.6% 16 36.4% 824 38.7%
 Invasive 9885 68.1% 866 63.8% 430 74.1% 165 64.5% 276 67.3% 21 47.7% 1,652 77.6%
 Invasive with prone position 5534 38.1% 534 39.3% 257 44.3% 101 39.5% 165 40.2% 14 31.8% 967 45.4%
Death (n, %) 4256 29.3% 347 25.6% 175 30.2% 45 17.6% 87 21.2% 12 27.3% 660 31.0%
  Hauts-de-France Ile-de-France Normandie Nouvelle-Aquitaine Occitanie Pays de la Loire Provence-Alpes-Côte D’azur
Population 2017 (n) 6,003,815 12,174,880 3,330,478 5,956,039 5,845,209 3,757,600 5,030,906
Patient in ICU—all causes (n) 5464 13,620 2451 4833 5142 2964 4683
Critically ill COVID-19 patients in ICU (n, %) 1333 24.4% 5650 41.5% 387 15.8% 503 10.4% 667 13.0% 355 12.0% 840 17.9%
Age class (n, %)               
 < 65 y.o 624 46.8% 3321 58.8% 177 45.7% 248 49.3% 286 42.9% 170 47.9% 351 41.8%
 65–79 y.o 579 43.4% 2016 35.7% 180 46.5% 212 42.1% 318 47.7% 166 46.8% 396 47.1%
 ≥ 80 y.o 130 9.8% 313 5.5% 30 7.8% 43 8.5% 63 9.4% 19 5.4% 93 11.1%
Age (mean ± s.d.) 63.9 ± 12.9 61 ± 13.2 63.6 ± 12.2 63.7 ± 12.6 64.2 ± 13.3 62.4 ± 13.2 65.3 ± 13.2
Sex ratio (M/F) 2.3 2.6 2.4 2.5 2.3 2.7 2.3
SAPS II (mean ± s.d.) 41.79 ± 18.6 38.76 ± 17.2 36.81 ± 14.8 39.5 ± 18.2 37.19 ± 16.1 35.95 ± 15.3 39.27 ± 15.6
Comorbidities (n, %) 1151 86.3% 4364 77.2% 326 84.2% 403 80.1% 537 80.5% 285 80.3% 680 81.0%
 High blood pressure 740 55.5% 2571 45.5% 207 53.5% 236 46.9% 306 45.9% 154 43.4% 404 48.1%
 Chronic heart disease 524 39.3% 1505 26.6% 140 36.2% 199 39.6% 245 36.7% 99 27.9% 323 38.5%
 Diabetes 413 31.0% 1746 30.9% 115 29.7% 135 26.8% 187 28.0% 87 24.5% 270 32.1%
 Obesity 358 26.9% 1286 22.8% 117 30.2% 121 24.1% 165 24.7% 88 24.8% 191 22.7%
 Cancer 420 31.5% 666 11.8% 78 20.2% 116 23.1% 186 27.9% 82 23.1% 213 25.4%
 Chronic renal disease 266 20.0% 627 11.1% 57 14.7% 85 16.9% 139 20.8% 51 14.4% 142 16.9%
 Chronic pulmonary disease 209 15.7% 535 9.5% 55 14.2% 82 16.3% 110 16.5% 34 9.6% 140 16.7%
 Neurological disease 102 7.7% 301 5.3% 16 4.1% 60 11.9% 75 11.2% 26 7.3% 59 7.0%
 Chronic liver disease 130 9.8% 352 6.2% 21 5.4% 31 6.2% 52 7.8% 22 6.2% 59 7.0%
ICU specific care supports (n, %)               
 Central venous catheter 695 52.1% 2700 47.8% 197 50.9% 284 56.5% 322 48.3% 161 45.4% 327 38.9%
 Continuous hemodynamic monitoring 799 59.9% 2726 48.2% 198 51.2% 318 63.2% 368 55.2% 144 40.6% 348 41.4%
 Vasoactive treatment* 746 56.0% 3234 57.2% 243 62.8% 315 62.6% 369 55.3% 192 54.1% 464 55.2%
Renal replacement therapy 212 15.9% 1007 17.8% 50 12.9% 57 11.3% 77 11.5% 46 13.0% 98 11.7%
ECMO 52 3.9% 306 5.4% 10 2.6% 7 1.4% 17 2.5% 20 5.6% 34 4.0%
Mechanical ventilation** (n, %)               
 Non invasive/high flow oxygenotherapy 696 52.2% 2450 43.4% 229 59.2% 229 45.5% 339 50.8% 99 27.9% 463 55.1%
 Invasive 849 63.7% 3823 67.7% 278 71.8% 334 66.4% 419 62.8% 242 68.2% 530 63.1%
 Invasive with prone position 389 29.2% 2158 38.2% 143 37% 143 28.4% 224 33.6% 137 38.6% 302 36.0%
Death (n, %) 406 30.5% 1894 33.5% 98 25.3% 93 18.5% 151 22.6% 80 22.5% 208 24.8%
  1. *Dobutamine, dopamine, epinephrine, norepinephrine
  2. **One patient can have both invasive and non-invasive mechanical ventilation during their ICU stay