Table 2 Factors associated with case fatality in COVID-19 patients admitted in the ICU in France, March, 1st to May, 31st 2020, analyzed by logistic regression model

Patient level

Age

 < 65 y–o

< .0001

Ref

 65–79 y–o

2.5

[2.3–2.8]

< .0001

 ≥ 80 y–o

10.2

[8.7–12]

< .0001

Sex

 Female

0.0009

1.1

[1–1.2]

0.16

SAPS II*

 < 30

 < .0001

Ref

 [30–40]

1.4

[1.3–1.6]

< .0001

 ≥ 40

2.3

[2.1–2.6]

< .0001

Comorbid conditions

 0

 < .0001

Ref

 1

1.0

[0.9–1.2]

0.9

 2

1.0

[0.9–1.1]

1.0

 ≥ 3

1.2

[1.0–1.3]

0.01

ICU specific care supports

 Invasive ventilation

< .0001

1.7

[1.5–1.9]

< .0001

 Vasoactive treatment**

< .0001

1.7

[1.5–1.9]

< .0001

 Renal replacement therapy

< .0001

2.9

[2.6–3.2]

< .0001

 ECMO

< .0001

2.9

[2.4–3.5]

< .0001

Hospital level

Number of ICU stays in hospital 2019, age ≥ 18 y–o***

< 100

0.003

1.3

[1.1–1.4]

 < .0001

 [1000–2000]

1.0

[0.9–1.2]

0.73

 ≥ 2000

Ref

Regional level

Number of days with 75% or more of ICU beds occupied by COVID-19 patients

 < 10 days

 < .0001

Ref

 10–19 days

1.2

[1.0–1.5]

0.03

 20–29 days

1.5

[1.2–1.7]

 < .0001

 ≥ 30 days

2.2

[1.9–2.6]

 < .0001