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Table 1 Demographics, clinical characteristics in four groups

From: Three broad classifications of acute respiratory failure etiologies based on regional ventilation and perfusion by electrical impedance tomography: a hypothesis-generating study

Variables

Control group

n = 15

PED group

n = 14

DLD group

n = 21

FLD group

n = 58

ANOVA-P value (Kruskal–Wallis test)

Age (years)

54 ± 14

59 (52, 68)

67 (55, 71)

65 (54, 75)

0.083

Sex (female/male)

6/9

10/4

9/12

21/37

N/A

APACHE II score

14 ± 5

15 (10, 17)

20 (15, 28)a, b

18 (14, 25)a, b

0.01

HR (bpm)

78 (65, 93)

87 (78, 93)

85 (80, 97)

94 (84, 103)a

0.019

MAP (mmHg)

87 ± 9

85 ± 10

84 ± 9

83 ± 12

0.336

FiO2 (%)

30 (30, 35)

45 (40, 80)a

40 (33, 58)a

40 (35, 75)a

< 0.0001

PaO2/FiO2 (mmHg)

390 (347, 474)

156 (86, 209)a

210 (117, 244)a

236 (170, 290)a, b

< 0.0001

d-Dimer (mg/L FEU)

1.0 (0.5, 3.0)

4.1 (2.7, 4.9)

4.6 (1.6, 6.2)

5.5 (1.9, 12.4)a

0.014

NE dose (μg/kg min)

0.00 (0.00, 0.09)

0.08 (0.00, 0.39)a

0.02 (0.00, 0.23)

0.08 (0.00, 0.26)

0.237

28-day mortality

0/15

4/14

3/21

11/58

N/A

  1. The control group was postoperative ICU patients without acute respiratory failure; PED group: patients with pulmonary embolism-related disease; DLD group: patients with diffuse lung involvement disease; FLD group: patients with focal lung involvement disease. Normally distributed results are presented as mean ± SD, whereas non-normally distributed results are presented as median (25th, 75th percentile)
  2. APACHE: Acute Physiology and Chronic Health Evaluation; HR: heart rate(bpm); MAP, mean arterial pressure (mmHg); PaO2: arterial partial pressure of oxygen; FiO2: fractional inspired oxygen concentration; N/A: not applicable
  3. aP < 0.05 vs. control group (adjusted by the Bonferroni correction for multiple test)
  4. bP < 0.05 vs. PED group (adjusted by the Bonferroni correction for multiple test)
  5. cP < 0.05 vs. DLD group (adjusted by the Bonferroni correction for multiple test)