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Table 2 Primary and secondary outcomes

From: High-flow nasal oxygen cannula vs. noninvasive mechanical ventilation to prevent reintubation in sepsis: a randomized controlled trial

Outcomes

NIV

(N = 110)

HFNC

(N = 112)

Relative risk

(95% CI)

P

Primary outcomes, No. (%)

 Reintubation at 72 h

20 (18.2)

20 (17.9)

0.99 (0.70–1.39)

0.95

Secondary outcomes, No. (%)

 Reintubation at 7 days

30 (27.3)

24 (21.4)

0.86 (0.64–1.14)

0.31

 Reintubation at 28 days

40 (36.4)

37 (33.0)

0.93 (0.71–1.22)

0.6

 Reintubation in ICU

37 (33.6)

33 (29.5)

0.91 (0.69–1.19)

0.5

 Extubation failure at 72 h

34 (30.9)

27 (24.1)

0.85 (0.64–1.12)

0.26

 Extubation failure in ICU

47 (42.7)

37 (33.0)

0.82 (0.63–1.06)

0.14

Mortality

 ICU mortality

12 (10.9)

6 (5.4)

0.72 (0.51–1.03)

0.13

 28-day mortality

10 (9.1)

8 (7.1)

0.88 (0.57–1.37)

0.59

 In-hospital mortality

26 (23.6)

24 (21.4)

0.94 (0.69–1.28)

0.69

Length of stay, median (IQR), days

 ICU length of stay

10 (6–22)

10 (6–19)

 

0.68

 Hospital length of stay

24 (14–44)

28 (19–48)

 

0.23