From: Admission serum myoglobin and the development of acute kidney injury after major trauma
Model 1 | Model 2 | |||||
---|---|---|---|---|---|---|
Base | Myoglobin | CK | Base | Myoglobin | CK | |
Estimation of baseline creatinine with MDRD formula | ||||||
OR (95% CI) | – | 1.017 (1.003–1.034) | 1.007 (0.999–1.042) | – | 1.026 (1.011–1.041) | 1.002 (0.999–1.028) |
p-value OR | – | 0.046 | 0.687 | – | < 0.001 | 0.866 |
AUC (95% CI) | 0.897 (0.861–0.931) | 0.902 (0.862–0.935) | 0.897 (0.860–0.931) | 0.798 (0.744–0.847) | 0.805 (0.752–0.856) | 0.799 (0.745–0.850) |
Estimation of baseline creatinine with creatinine on admission | ||||||
OR (95% CI) | – | 1.017 (1.003–1.032) | 1.019 (0.999–1.043) | – | 1.011 (0.999–1.025) | 0.999 (0.998–1.002) |
p-value OR | – | 0.019 | 0.137 | – | 0.15 | 0.717 |
AUC (95% CI) | 0.745 (0.691–0.794) | 0.759 (0.705–0.808) | 0.746 (0.690–0.801) | 0.767 (0.714–0.811) | 0.769 (0.718–0.815) | 0.766 (0.745–0.837) |
Estimation of baseline creatinine with lowest creatinine over the first 5 days | ||||||
OR (95% CI) | – | 1.050 (1.035–1.065) | 1.063 (1.039–1.086) | – | 1.034 (1.019–1.050) | 1.033 (1.010–1.056) |
p-value OR | – | < 0.001 | < 0.001 | – | < 0.001 | 0.006 |
AUC (95% CI) | 0.654 (0.616–0.694) | 0.773 (0.739–0.806) | 0.681 (0.642–0.718) | 0.782(0.748–0.816) | 0.798 (0.764–0.830) | 0.787 (0.758–0.822) |