Table 3 Performances of admission myoglobin and CK to predict severe rhabdomyolysis
From: Admission serum myoglobin and the development of acute kidney injury after major trauma
Performance parameter | Prediction of severe rhabdomyolysis defined by a maximum myoglobin > 5000 μg/L | Prediction of severe rhabdomyolysis defined by a maximum CK > 5000 U/L | ||
|---|---|---|---|---|
Admission myoglobin | Admission CK | Admission myoglobin | Admission CK | |
AUC-ROC | 0.94 (0.91–0.97)* | 0.88 (0.84–0.91)* | 0.91 (0.88–0.94)# | 0.88 (0.85–0.91)# |
Optimal cutoff | 1938 | 850 | 1193 | 686 |
Sensitivity | 84 (74–91) | 83 (72–90) | 85 (77–90) | 88 (81–93) |
Specificity | 90 (88–92) | 80 (77–83) | 84 (81–87) | 75 (72–78) |
PPV | 41 (33–49) | 25 (20–32) | 45 (39–52) | 35 (30–41) |
NPV | 99 (97–99) | 98 (97–99) | 97 (96–98) | 98 (96–99) |
PLR | 8.5 (6.7–10.7) | 4.2 (3.5–5.0) | 5.4 (4.5–6.5) | 3.6 (3.1–4.1) |
NLR | 0.2 (0.1–0.3) | 0.2 (0.1–0.4) | 0.2 (0.1–0.3) | 0.2 (0.1–0.3) |