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Table 2 Multivariable risk-adjusted predictive model for short- and long-term mortality

From: Long-term survival of mechanically ventilated patients with severe COVID-19: an observational cohort study

Variables

ICU Mortality OR (95% CI)

Hospital Mortality OR (95% CI)

28-day Mortality OR (95% CI)

Age, (per 1-year increase)

1.049 (1.032–1.066)

1.050 (1.033–1.068)

1.058 (1.035–1.081)

Male

   

Diabetes mellitus

 

1.546 (1.084–2.203)

1.626 (1.093–2.420)

Chronic steroids

  

3.697 (1.633–8.371)

SAPS3, (per 1-point increase)

1.025 (1.008–1.041)

1.027 (1.011–1.044)

 

N:L ratio (per 1-unit increase)

1.009 (1.002–1.016)

1.008 (1.000–1.016)

 

Failed attempt of NPPV prior to orotracheal intubation

2.131 (1.279–3.550)

1.878 (1.123–3.39)

 

Selective Digestive Decontamination strategy

0.587 (0.358–0.963)

0.591 (0.358–0.972)

 

Need of vasopressor support

1.878 (1.119–3.152)

2.042 (1.205–3.460)

2.158 (1.197–3.891)

Methylprednisolone < 1 mg/kg

  

0.500 (0.302–0.828)

Methylprednisolone > 1 mg/kg

  

0.479 (0.283–0.811)

AUC (95% CI)

0.712 (0.677; 0.746)

0.728

(0.694; 0.761)

0.746 (0.705; 0.787)

Calibration, CITL (95% CI)

0.001 (-0.306; 0.308)

0.0007

(-0.312;0.313)

 < 0.001 (-0.398; 0.398)

Slope (95% CI)

1.025 (0.822; 1.228)

1.018 (0.827; 1.209)

1.000 (0.788; 1.214)

  1. SAPS, Simplified Acute Physiology Score; NPPV: noninvasive positive pressure ventilation; N: L, neutrophil to lymphocyte ratio; AUC; area under the curve. OR, Odds Ratio; CI, confidence interval