PCT Group (n = 81) | Control group (n = 78) | p | Adjusted p* | |
---|---|---|---|---|
Suspected site of infection (at 7 days) | ||||
Lungs | 30 (37) | 25 (32) | 0.51 | 0.68 |
Urinary tract | 2 (3) | 4 (5) | 0.44 | 0.26 |
Digestive tract | 1 (1) | 0 | 1 | 0.95 |
Catheter | 1 (1) | 0 | 1 | 0.95 |
Other | 6 (7) | 3 (4) | 0.5 | 0.53 |
Severity criteria | ||||
Severe sepsis | 5 (7) | 7 (13) | 0.3 | 0.23 |
Septic shock | 4 (6) | 3 (5) | 1 | 0.72 |
No. exposed to antibiotics | 37 (46) | 30 (40) | 0.43 | 0.61 |
Timing between admission to ICU and initiation of antibiotics (days) | 1.3 ± 2.4 | 1.5 ± 2.9 | 0.74 | 0.72 |
No. of days on antibiotics during first week | 2.1 ± 2.5 | 1.7 ± 2.3 | 0.31 | 0.37 |
No. of days on antibiotics during first 15 days | 3.0 ± 4.1 | 2.3 ± 3.4 | 0.31 | 0.41 |
Antibiotic consumption in total DDD in ICU | 11.5 ± 22.4 | 8.0 ± 14.7 | 0.3 | 0.48 |
No. of antibiotic-free days up to 15 days | 13 ± 2.7 | 13.5 ± 2.9 | 0.30 | 0.38 |