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Table 2 Details of infections and antibiotic prescriptions

From: Impact on antimicrobial consumption of procalcitonin-guided antibiotic therapy for pneumonia/pneumonitis associated with aspiration in comatose mechanically ventilated patients: a multicenter, randomized controlled study

  PCT Group (n = 81) Control group (n = 78) p Adjusted p*
Suspected site of infection (at 7 days)
 Lungs 30 (37) 25 (32) 0.51 0.68
 Urinary tract 2 (3) 4 (5) 0.44 0.26
 Digestive tract 1 (1) 0 1 0.95
 Catheter 1 (1) 0 1 0.95
 Other 6 (7) 3 (4) 0.5 0.53
Severity criteria
 Severe sepsis 5 (7) 7 (13) 0.3 0.23
 Septic shock 4 (6) 3 (5) 1 0.72
No. exposed to antibiotics 37 (46) 30 (40) 0.43 0.61
Timing between admission to ICU and initiation of antibiotics (days) 1.3 ± 2.4 1.5 ± 2.9 0.74 0.72
No. of days on antibiotics during first week 2.1 ± 2.5 1.7 ± 2.3 0.31 0.37
No. of days on antibiotics during first 15 days 3.0 ± 4.1 2.3 ± 3.4 0.31 0.41
Antibiotic consumption in total DDD in ICU 11.5 ± 22.4 8.0 ± 14.7 0.3 0.48
No. of antibiotic-free days up to 15 days 13 ± 2.7 13.5 ± 2.9 0.30 0.38
  1. PCT procalcitonin, No. number, DDD Defined Daily Doses
  2. *Adjusted for SAPS II score