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Table 2 Details of infections and antibiotic prescriptions

From: Impact on antimicrobial consumption of procalcitonin-guided antibiotic therapy for pneumonia/pneumonitis associated with aspiration in comatose mechanically ventilated patients: a multicenter, randomized controlled study

 

PCT Group (n = 81)

Control group (n = 78)

p

Adjusted p*

Suspected site of infection (at 7 days)

 Lungs

30 (37)

25 (32)

0.51

0.68

 Urinary tract

2 (3)

4 (5)

0.44

0.26

 Digestive tract

1 (1)

0

1

0.95

 Catheter

1 (1)

0

1

0.95

 Other

6 (7)

3 (4)

0.5

0.53

Severity criteria

 Severe sepsis

5 (7)

7 (13)

0.3

0.23

 Septic shock

4 (6)

3 (5)

1

0.72

No. exposed to antibiotics

37 (46)

30 (40)

0.43

0.61

Timing between admission to ICU and initiation of antibiotics (days)

1.3 ± 2.4

1.5 ± 2.9

0.74

0.72

No. of days on antibiotics during first week

2.1 ± 2.5

1.7 ± 2.3

0.31

0.37

No. of days on antibiotics during first 15 days

3.0 ± 4.1

2.3 ± 3.4

0.31

0.41

Antibiotic consumption in total DDD in ICU

11.5 ± 22.4

8.0 ± 14.7

0.3

0.48

No. of antibiotic-free days up to 15 days

13 ± 2.7

13.5 ± 2.9

0.30

0.38

  1. PCT procalcitonin, No. number, DDD Defined Daily Doses
  2. *Adjusted for SAPS II score