Transesophageal echocardiography for cardiovascular risk estimation in patients with sepsis and new-onset atrial fibrillation: a multicenter prospective pilot study

Annals of Intensive Care

Table 4 Univariate and multivariable analyses of factors associated with cardiovascular events^a

Variable	Univariate analysis		Multivariable analysis
Variable	HR (95% CI)	p value	HR (95% CI)	p value
Septic shock^b	2.72 (1.30–5.69)	0.01	2.36 (1.06–5.29)	0.04
Electrical cardioversion attempt^b	2.33 (1.17–4.65)	0.02	1.51 (0.72–3.17)	0.27
LV systolic dysfunction^{c, d}	2.75 (1.48–5.08)	0.001	2.06 (1.05–4.05)	0.03
LA/LAA dysfunction^d, ^e	1.14 (0.54–2.39)	0.73	0.85 (0.39–1.87)	0.69
Severe aortic atheroma^d	0.58 (0.26–1.33)	0.20	0.60 (0.26–1.40)	0.24

CI confidence interval, HR hazard ratio, LA left atrial, LAA left atrial appendage, LV left ventricular
^aComposite of arterial thromboembolic events, major bleeding events, and death from any cause
^bOn the first day of new-onset atrial fibrillation onset
^cLV ejection fraction ≤ 45%
^dAt the first echocardiography
^eLA/LAA dense spontaneous echo contrast or LAA low velocity