Table 2 Serotype distribution and antibiotic susceptibility according to initial blood culture results
Variable | Positive blood culture (N = 212) | Negative blood culture (N = 127) | p value | Adjusted p valuea |
|---|---|---|---|---|
Serotype, n (%) | < 0.0001 | 0.003 | ||
3 | 45 (21.2) | 36 (28.3) | ||
7F | 38 (17.9) | 14 (11.0) | ||
19A | 31 (14.6) | 18 (14.2) | ||
12F | 19 (9.0) | 3 (2.4) | ||
1 | 19 (9.0) | 2 (1.6) | ||
6C | 6 (2.8) | 4 (3.1) | ||
11A | 1 (0.5) | 9 (7.1) | ||
Other | 53 (25.0) | 41 (32.3) | ||
Serotype invasivenessb, n (%) | 0.002 | 0.002 | ||
High | 166 (78.3) | 78 (61.4) | ||
Low | 13 (6.1) | 20 (15.7) | ||
Undetermined | 33 (15.6) | 29 (22.8) | ||
Serotype case fatality ratec, n (%) | < 0.0001 | < 0.0001 | ||
Low | 72 (34.0) | 19 (15.0) | ||
Intermediate | 30 (14.2) | 11 (8.7) | ||
High | 102 (48.1) | 86 (67.7) | ||
Other | 8 (3.8) | 11 (8.7) | ||
Penicillin susceptible, n (%) | 168 (79.2) | 92 (72.4) | 0.18 | 0.14 |
Amoxicillin susceptible, n (%) | 198 (93.4) | 107 (84.3) | 0.009 | 0.010 |
Cefotaxime susceptible, n (%) | 206 (97.2) | 123 (96.9) | > 0.99 | 0.70 |
Erythromycin susceptible, n (%) | 163 (76.9) | 93 (73.2) | 0.51 | 0.41 |
Levofloxacin susceptible, n (%) | 210 (99.1) | 127 (100.0) | 0.53 | – |