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Table 4 Associations of baseline variables with hospital deaths in the groups with and without bacteraemia

From: Comparison of prognostic factors between bacteraemic and non-bacteraemic critically ill immunocompetent patients in community-acquired severe pneumococcal pneumonia: a STREPTOGENE sub-study

Variable

Positive blood culture (N = 270)

Negative blood culture (N = 344)

p value (interaction)

Age (years)

 18–50

1

1

 51–65

1.70 (0.56 to 5.12)

0.77 (0.21 to 2.76)

0.36

 > 65

4.32 (1.47 to 12.7)

2.33 (0.70 to 7.77)

0.45

Male gender

1.70 (0.79 to 3.67)

1.84 (0.85 to 3.98)

0.89

McCabe score ≥ 2

1.23 (0.42 to 3.61)

4.03 (1.24 to 13.2)

0.14

SAPS II (per unit)

1.04 (1.01 to 1.07)

1.04 (1.02 to 1.07)

0.79

Platelets ≤ 100 × 109/L

1.59 (0.62 to 4.10)

2.66 (1.02 to 6.92)

0.24

Lactates (mmol/L)

 < 2

1

1

 2–4

0.76 (0.28 to 2.04)

1.77 (0.65 to 4.84)

0.18

 > 4

1.50 (0.52 to 4.34)

4.29 (1.45 to 12.7)

0.46

Bilateral pulmonary infection

1.63 (0.77 to 3.43)

1.90 (0.93 to 3.88)

0.77

Shock

2.19 (0.86 to 5.59)

1.95 (0.86 to 4.40)

0.85

Invasive mechanical ventilation

1.11 (0.38 to 3.21)

3.06 (1.24 to 7.59)

0.15

Pre-hospital antibiotic therapy

1.20 (0.35 to 4.06)

1.09 (0.41 to 2.91)

0.91

Time to antibiotics (h)

 < 3

1

1

 3–6

0.56 (0.19 to 1.59)

0.73 (0.27 to 2.02)

0.71

 > 6

1.23 (0.50 to 3.02)

1.66 (0.71 to 3.90)

0.63

  1. SAPS II Simplified Acute Physiology Score II