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Table 2 Comorbidities of the study population

From: Characteristics of Sepsis-2 septic shock patients failing to satisfy the Sepsis-3 septic shock definition: an analysis of real-time collected data

 

95% CI

p

 

S3+ 

S2+ /S3–

Absolute difference

Lower bound

Upper bound

Nicotine

194 (25.5)

67 (33.8)

 − 8.3

 − 15.7

 − 1.1

0.019

Alcohol abuse

152 (18.5)

23 (11.3)

7.2

1.8

12.0

0.014

NYHA III/IV

242 (26.6)

70 (31.3)

 − 4.7

 − 11.5

1.9

0.159

Organ transplantation

19 (5.1)

8 (10.5)

 − 5.4

 − 13.6

1.3

0.074

Stem cell transplantation

7 (1.9)

0 (0)

1.9

 − 2.0

3.8

0.226

Malignancy

174 (28.9)

50 (21.6)

7.3

1.0

13.1

0.026

Metastatic malignancy

100 (10.6)

18 (7.8)

2.8

 − 1.5

6.5

0.209

Hematologic condition

111 (11.7)

41 (17.7)

 − 6.1

 − 11.6

 − 0.9

0.013

Chronic Liver disease

153 (16.2)

13 (5.6)

10.6

6.4

14.1

 < 0.001

Pulmonary disease

162 (17.2)

54 (23.3)

 − 6.1

 − 12.2

 − 0.3

0.032

Chronic kidney disease

206 (21.7)

63 (27.3)

 − 5.6

 − 12.0

0.6

0.071

Patient on dialysis

24 (2.5)

11 (4.8)

 − 2.2

 − 5.5

0.5

0.073

Diabetes mellitus

202 (21.2)

48 (20.7)

0.5

 − 5.5

6.2

0.854

Hypertension

305 (32.2)

78 (33.8)

 − 1.6

 − 8.5

5.1

0.643

Vascular disease

160 (16.9)

45 (19.5)

 − 2.6

 − 8.4

2.8

0.349

Ischemic stroke

50 (5.3)

11 (4.8)

0.5

 − 3.0

3.4

0.753

Coronary disease

180 (19.1)

45 (19.4)

 − 0.3

 − 6.2

5.2

0.909

  1. All values are expressed as median (IQR) or n (%). NYHA: New York Heart Association Scale