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Table 1 Characteristics of the cohort and outcomes

From: Impact of obesity on survival in COVID-19 ARDS patients receiving ECMO: results from an ambispective observational cohort

 

76 patients

Patient ‘s characteristics

 Comorbidities, n (%)

  Obesitya

29 (38%)

  Hypertension

32 (42.1%)

  Diabetes

28 (36.8%)

  Coronary artery disease

9 (11.8%)

  Dyslipidemia

16 (21.1%)

  Smoking

15 (19.7%)

  Immunosuppression

5 (6.6%)

  Chronic lung disease

9 (11.8%)

  Chronic kidney disease

4 (5.3%)

  Number of comorbidities

0 (0–1)

Type of ECMO support, n (%)

 Veno-venous

75 (98.7%)

 Arteriovenous

1 (1.3%)

Cardiac arrest before ECMO, n (%)

4 (5.3%)

 Outcome

  ECMO weaning, n (%)

45 (59.2%)

  ECMO second run, n (%)

5 (6.6%)

  ECMO-free days at D60

14 (0–36.5)

  MV duration

41 (27.5–54.5)

  Mortality, n (%)

    Day 28

6 (7.9%)

    Day 60

29 (38.2%)

    Day 90

37 (48.7%)

  Length of stay in ICU, (days)

47.5 (33–65)

  Length of stay in hospital, (days)

50 (38–80)

Complications during ICU stay, n (%)

 Invasive aspergillosis

4 (5.3%)

 Viral reactivation

  CMV

32 (43.2%)

   Antiviral treatment

30 (94%)

  HSV

21 (28.4%)

   Antiviral treatment

15 (71%)

Cause of death, n (%)

 Septic shock

13 (17.1%)

 Hemorrhagic shock

12 (15.8%)

 Cardiogenic shock

1 (1.3%)

 Stroke

2 (2.6%)

 Multi-organ failure

3 (3.9%)

 Other

6 (7.9%)

  1. Data are expressed as median (interquartiles) or number (percentage, %)
  2. Obesity was defined by a BMI superior or equal to 30 g/m2
  3. BMI body mass index, NSAID non-steroidal anti-inflammatory drug, ACE angiotensin converting enzyme, ARB angiotensin II receptor blockers, SAPS II Simplified Acute Physiology score, SOFA Sequential Organ Function, ICU intensive care unit, ECMO extra-corporeal membrane oxygenation, MV mechanical ventilation, CMV cytomegalovirus, HSV herpes simplex virus
  4. a3 patients had missing data for BMI